Summaries & Associations of Study Results
TR-428 Manganese Sulfate Monohydrate
Target Organs and Levels of Evidence
NTP Technical Report Number 428
Produced from Chemtrack Database 09/19/01
| CHEMICAL/ CAS NUMBER | PEER REVIEW DATE | PRIMARY USES | ROUTE/EXPOSURE LEVELS | STUDY LABORATORY |
|---|---|---|---|---|
| MANGANESE SULFATE MONOHYDRATE 10034-96-5 |
06/23/92 | FERTILIZERS. FEED ADDITIVE. INTERMEDIATE IN PAINTS, VARNISHES, CERAMICS, TEXTILE DYES, AND MEDICINES. (2) | Dosed-Feed R & M: 0, 1500, 5000, AND 15000 PPM/50 PER GROUP | Battelle Columbus Laboratory |
| LEVELS OF EVIDENCE OF CARCINOGENICITY--ORGAN/TISSUE (NEOPLASM): | ||||
| MR: NO EVIDENCE | ||||
| NON-NEOPLASTIC LESIONS: | KIDNEY: INCREASED SEVERITY OF NEPHROPATHY | |||
| FR: NO EVIDENCE | ||||
| MM: EQUIVOCAL EVIDENCE | THYROID GLAND FOLLICULAR CELL: ADENOMA 0/50 0/49 0/51 3/50 | |||
| NON-NEOPLASTIC LESIONS: | FORESTOMACH: FOCAL HYPERPLASIA; ULCER; INFLAMMATION | |||
| THYROID GLAND: FOLLICULAR CELL HYPERPLASIA | ||||
| FM: EQUIVOCAL EVIDENCE | THYROID GLAND FOLLICULAR CELL: ADENOMA 2/50 1/50 0/49 5/51 | |||
| NON-NEOPLASTIC LESIONS: | THYROID GLAND: FOLLICULAR CELL HYPERPLASIA | |||
| FORESTOMACH: FOCAL HYPERPLASIA | ||||
Web page last updated on February 10, 2006
