National Toxicology Program

• Background
  • CAS # 87-86-5
  • General biocide that has been used extensively as a fungicide, bactericide, herbicide and insecticide by agriculture and other industries. In 1987, over-the-counter use was banned and other uses restricted. The only current use of pentachlorophenol in the United States is defined as a ‘heavy duty’ wood preservative that is used primarily in the treatment of utility poles and cross arms.

• RoC documents related to the scientific review of pentachlorophenol
  • Federal Register Notice - Jan. 19, 2012 requesting public comment on nominated substances
  • Concept Document
  • Federal Register Notice – October 17 2012 requesting Nominations of Scientific Experts
  • Protocol: Evaluation of cancer studies in experimental animals (November 2, 2012)
  • Preliminary literature search and identified citations
  • Draft RoC Monograph
  • Final RoC Monograph

• Public Comments

• Meetings, Webinars and Listening Sessions
• Webinar (April 11, 2013) - Human cancer studies on exposure to pentacholorophenol (PCP): Differentiating potential cancer effects of PCP exposure from effects due to occupational co-exposures or PCP contaminants


• INPUT – provide information (such as citations or new studies, scientific issues, nomination of experts or to comment on RoC documents)

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