National Toxicology Program

CASRN: 56802-99-4

Formula: (Na3-PO4·12H2O)4·Na-O-Cl

Synonyms/Common Names:

• SODIUM HYPOCHLORITE PHOSPHATE

Known Uses:

Detergent and bactericide in food and dairy processing, in automatic dishwasher detergent, scouring cleansers, laundry soaps (HSDB 1990).

Short-Term Toxicity

• 14-Day (Gavage)  (C55754A)  Completed 
  • Rats: F344/N; Mice: B6C3F1
• 13-Week (Gavage)  (C55754A)  Completed 
  • Rats: F344/N; Mice: B6C3F1
  • Dose: R: 0,62,1000 M: 0,31,500 MG/KG/10 PER GROUP.

Long-Term Carcinogenicity

• 2-YEAR (Gavage)  (C55754A)  Report Complete 
  • TR-294 (NIH Number: 87-2550; NTIS Number: PB87-189718)  (Peer Review Approval 11/02/1984A )
    Toxicology and Carcinogenesis Studies of Chlorinated Trisodium Phosphate (CASRN 56802-99-4) in B6C3F1 Mice (Gavage Studies)
  • Mice: B6C3F1
  • Carcinogenesis Results
  • Male Rats Inadequate Study 
  • Female Rats Inadequate Study 
  • Male Mice No Evidence 
  • Female Mice No Evidence 
  • Dose: R: 0,500,1000,2000 M: 0,250,500,1000 MG/KG/50 PER GROUP.
• 2-Year (Gavage)  (C55754A)  Report Complete 
  • TR-294 (NIH Number: 87-2550; NTIS Number: PB87-189718)  (Peer Review Approval 11/02/1984A )
    Toxicology and Carcinogenesis Studies of Chlorinated Trisodium Phosphate (CASRN 56802-99-4) in B6C3F1 Mice (Gavage Studies)
  • Rats: F344/N
  • Carcinogenesis Results
  • Male Rats Inadequate Study 
  • Female Rats Inadequate Study 
  • Male Mice No Evidence 
  • Female Mice No Evidence 
  • Dose: R: 0,500,1000,2000 M: 0,250,500,1000 MG/KG/50 PER GROUP.

Genetic Toxicology

• In Vitro Cytogenetics (CA/SCE)  (387936)  Completed 
  • Citation: Loveday, K.S., Lugo, M.H., Resnick, M.A., Anderson, B., and Zeiger, E. Chromosome aberration and sister chromatid exchange tests in Chinese hamster ovary cells in vitro II: Results with 20 chemicals Environ. Molec. Mutagen. Vol. 13 (1989) 60-94
  • Sister Chromatid Exchange Positive 
  • Chromosome Aberation Positive 
• Salmonella  (610291)  Completed 
  • Citation: Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelmans, K. Salmonella mutagenicity tests. IV. Results from the testing of 300 chemicals Environ. Molec. Mutagen. Vol. 11 (Suppl 12) (1988) 1-158
  •  Weakly Positive