Testing Information

Testing Status of Agents at NTP

Perfluorooctane Sulfonate, PFOS

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http://ntp.niehs.nih.gov/go/TS-M040004

CASRN: 1763-23-1

Formula: C8-H-F17-O3-S

Synonyms/Common Names:

  • C8 SULFONATE
  • HEPTADECAFLUOROOCTANE-1-SULPHONIC ACID
  • 1-OCTANESULFONIC ACID, 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-HEPTADECAFLUORO
  • PERFLUOROOCTANE SULFONIC ACID

Known Uses:

Surface-active agents in aqueous media. Chemical intermediate; acid catalyst for photoresists surfactant in fire fighting foam; surfactant for alkaline cleaners; emulsifier in floor polish; mist suppressant for metal plating baths; surfactant for etching acids for circuit boards; pesticide active ingredient for ant bait traps.

Nomination Background

Planned Carcinogenicity/Toxicity

  • 4-WEEK (Gavage) Selected (C20617)  
    • Rats: Sprague Dawley

Genetic Toxicology

  • Salmonella  (A33826) Completed 
    •  Negative 

Organ Systems Toxicity

  • GD 6 to PND 21 Conventional Teratology (Gavage) Selected (R04046)  
    • Rats: Sprague Dawley