Special Senses System

Harderian Gland - Inflammation

    Narrative
    Harderian gland - Inflammation, Chronic active in a female Sprague- Dawley rat from a chronic study. Numerous inflammatory cells are present in the interstitium and alveoli with destruction of the acinar tissue.
    Harderian gland - Inflammation, Chronic active in a female Sprague- Dawley rat from a chronic study. Numerous inflammatory cells are present in the interstitium and alveoli with destruction of the acinar tissue.
    Harderian gland - Inflammation, Chronic active in a female Sprague- Dawley rat from a chronic study (higher magnification of Figure 1). The inflammatory cells, largely neutrophils and macrophages expand the interstitium and infiltrate the alveoli, many of which are necrotic.
    Harderian gland - Inflammation, Chronic active in a female Sprague- Dawley rat from a chronic study (higher magnification of Figure 1). The inflammatory cells, largely neutrophils and macrophages expand the interstitium and infiltrate the alveoli, many of which are necrotic.
    Harderian gland - Inflammation, Suppurative in a male B6C3F1 mouse from a chronic study. There are massive accumulations of neutrophils (arrow) with necrotic debris (asterisk) in the alveolar lumens and interstitium with destruction of the normal architecture.
    Harderian gland - Inflammation, Suppurative in a male B6C3F1 mouse from a chronic study. There are massive accumulations of neutrophils (arrow) with necrotic debris (asterisk) in the alveolar lumens and interstitium with destruction of the normal architecture.
    Harderian gland - Inflammation, Chronic in a female B6C3F1 mouse from a chronic study. There are macrophages and lymphocytes (predominantly). interstitial fibrosis, and foreign bodies (hair shaft fragments) (arrow) in the Harderian gland.
    Harderian gland - Inflammation, Chronic in a female B6C3F1 mouse from a chronic study. There are macrophages and lymphocytes (predominantly). interstitial fibrosis, and foreign bodies (hair shaft fragments) (arrow) in the Harderian gland.

    Author

    Margarita M. Gruebbel, DVM, PhD, DACVP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Reviewers

    Ruth E. Hurley, DVM, PHD, DACVP
    Senior Veterinary Pathologist
    Huntingdon Life Sciences
    North Brunswick, NJ

    Robert R. Maronpot, DVM, MS, MPH, DACVP, DABT, FIATP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC