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Chlordecone (143-50-0)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID1020770


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
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  • Positive, Male, Rats
View
  • Positive, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
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  • Positive, Male, Mice
View
  • Positive, Female, Mice

Genetic Toxicology

An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to Chlordecone (143-50-0).
Mammalian Cell Mutagenicity
View
  • Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to Chlordecone (143-50-0).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Chlordecone (143-50-0).
Bacterial Mutagenicity
View
  • Negative
View
  • Negative

Citation Information


NTP. Chlordecone (143-50-0). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-000 (143-50-0) Report on Carcinogenesis Bioassay of Technical Grade Chlordecone (Kepone) (CASRN 143-50-0)
Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
Galloway, S., Armstrong, M., Reuben, C., Colman, S., Brown, B., Cannon, C., Bloom, A., Nakamura, F., Ahmed, M., Duk, S., Rimpo, J., Margolin, B., Resnick, M., Anderson, B., and Zeiger, E. Chromosome aberration and sister chromatid exchanges in Chinese hamster ovary cells: Evaluations of 108 chemicals. Environ. Molec. Mutagen. Vol. 10 (Suppl 10) (1987) 1-176

Study Data


Toxicity and Carcinogenicity Studies


Evaluation of the Chronic Toxicity and Carcinogenicity of Chlordecone (Kepone) (143-50-0) in Male Osborne-Mendel Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of Chlordecone (Kepone) (143-50-0) in Female Osborne-Mendel Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of Chlordecone (Kepone) (143-50-0) in Male B6C3F1 Mice Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of Chlordecone (Kepone) (143-50-0) in Female B6C3F1 Mice Exposed via Dosed Feed

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Chlordecone (Kepone) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 663576
Summary Data
Genetic Toxicity Evaluation of Chlordecone (Kepone) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 795821
Summary Data