Caprolactam (105-60-2)
DOI: https://doi.org/10.22427/NTP-DATA-DTXSID4020240
Study Results
Chronic Bioassay Level of Evidence
Rats | |
---|---|
View
|
|
View
|
Mice | |
---|---|
View
|
|
View
|
Genetic Toxicology
Rodent Cytogenetics | |
---|---|
CA | SCE |
|
|
Micronucleus - Mice |
---|
View
|
Mammalian Cell Mutagenicity |
---|
View
|
Mammalian Cell Cytogenetics | |
---|---|
CA | SCE |
|
|
Drosophila Germ Cell Mutagenicity |
---|
SLRL |
|
Bacterial Mutagenicity |
---|
View
|
Publications
TR-214
Carcinogenesis Bioassay of Caprolactam (CASRN 105-60-2) in F344 Rats and B6C3F1 Mice (Feed Study)
McFee, A.F., and Lowe, K.W. Caprolactam and benzoin: tests for induction of chromosome aberrations and sister-chromatid exchanges in mouse bone marrow. Mutation Res. Vol. 224 (1989) 347-350
Zeiger, E., and Haworth, S. Tests with a preincubation modification of the Salmonella/microsome assay. In Evaluation of Short-Term Tests for Carcinogens Elsevier/North Holland 187-199
Shelby, M.D., Erexson, G.L., Hook, G.J., and Tice, R.R. Evaluation of a three-exposure mouse bone marrow micronucleus protocol: Results with 49 chemicals. Environ. Molec. Mutag. Vol. 21 (1993) 160-179
Myhr, B., Bower, L., and Caspary, W. Assays for the induction of gene mutations at the thymine kinase locus in L1578Y mouse lymphoma cells in culture. In Evaluation of Short-Term Tests for Carcinogens, Elsevier/North Holland Vol. (1985) 555-568
Foureman, P., Mason, J.M., Valencia, R., Zimmering, S. Chemical Mutagenesis Testing in Drosophila. IX. Results of 50 coded compounds tested for the National Toxicology Program. Environ. Molec. Mutagen. Vol. 23 (1994) 51-63
Gulati, D., Sabharwal, P., and Shelby, M. Tests for the induction of chromosomal aberrations and sister chromatid exchanges in cultured Chinese hamster ovary (CHO) cells. In Evaluation of Short-Term Tests for Carcinogens, Elsevier/North Holland 413-426
Gulati, D., Witt, K., Anderson, B., Zeiger, E.,and Shelby, M. Chromosome aberration and sister chromatid exchange test in Chinese hamster ovary cells in vitro III: Results with 27 chemicals Environ. Molec. Mutagen. Vol. 13 (1989) 133-193
McFee, A.F., and Lowe, K.W. Caprolactam and benzoin: tests for induction of chromosome aberrations and sister-chromatid exchanges in mouse bone marrow. Mutation Res. Vol. 224 (1989) 347-350
Study Data
Toxicity and Carcinogenicity Studies
Evaluation of the Chronic Toxicity and Carcinogenicity of Caprolactam (105-60-2) in Male F344 Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of Caprolactam (105-60-2) in Female F344 Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of Caprolactam (105-60-2) in Male B6C3F1 Mice Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of Caprolactam (105-60-2) in Female B6C3F1 Mice Exposed via Dosed Feed
Genetic Toxicology Studies
Genetic Toxicity Evaluation of Caprolactam (105-60-2) in Micronucleus Study 222213 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Caprolactam in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 572383
Summary Data
- G06 - Ames Summary Data (144 KB)