Diethanolamine (111-42-2)
DOI: https://doi.org/10.22427/NTP-DATA-DTXSID3021932
Study Results
Chronic Bioassay Level of Evidence
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| Mice | |
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Genetic Toxicology
| Micronucleus - Mice |
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| Mammalian Cell Mutagenicity |
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| Mammalian Cell Cytogenetics | |
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| CA | SCE |
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| Bacterial Mutagenicity |
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Publications
TR-478
Toxicology and Carcinogenesis Studies of Diethanolamine (CASRN 111-42-2) in F344/N Rats and B6C3F1 Mice (Dermal Studies)
TOX-20
Toxicity Studies of Diethanolamine (CASRN 111-42-2) Administered Topically and in Drinking Water to F344/N Rats and B6C3F1Mice
Haworth, S., Lawlor, T., Mortelmans, K., Speck, W., and Zeiger, E. Salmonella mutagenicity test results for 250 chemicals Environ. Mutagen. Vol. 5 (Suppl 1) (1983) 3-142
Developmental Toxicity Screen for Diethanolamine (CASRN 111-42-2) Administered by Gavage to Sprague-Dawley (CD®) Rats on Gestational Days 6 through 19: Evaluation of Dams and Pups through Postnatal Day 21
Witt, K.L., Knapton, A., Wehr, C.M., Hook, G.J., Mirsalis, J., Shelby, M.D., and MacGregor, J.T. Micronucleated Erythrocyte Frequency in Peripheral Blood of B6C3F1 Mice from Short-Term, Prechronic, and Chronic Studies of the NTP Carcinogenesis Bioassay Program. Environ. Molec. Mutagen. Vol. 36 (2000) 163-194
Loveday, K.S., Lugo, M.H., Resnick, M.A., Anderson, B., and Zeiger, E. Chromosome aberration and sister chromatid exchange tests in Chinese hamster ovary cells in vitro II: Results with 20 chemicals Environ. Molec. Mutagen. Vol. 13 (1989) 60-94
Study Data
Toxicity and Carcinogenicity Studies
3-Month Evaluation of the Toxicity (C55174B) of Diethanolamine (111-42-2) in F344/N Rats Exposed via Topical Application
Pathology Tables
Individual Animal Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
3-Month Evaluation of the Toxicity (C55174C) of Diethanolamine (111-42-2) in F344/N Rats Exposed via Dosed Water
Pathology Tables
Individual Animal Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
3-Month Evaluation of the Toxicity (C55174B) of Diethanolamine (111-42-2) in B6C3F1 Mice Exposed via Topical Application
Pathology Tables
Individual Animal Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
3-Month Evaluation of the Toxicity (C55174C) of Diethanolamine (111-42-2) in B6C3F1 Mice Exposed via Dosed Water
Pathology Tables
Individual Animal Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
Evaluation of the Chronic Toxicity and Carcinogenicity (C55174D) of Diethanolamine (111-42-2) in F344/N Rats Exposed via Topical Application
Pathology Tables
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Neoplastic
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Neoplastic
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
Evaluation of the Chronic Toxicity and Carcinogenicity (C55174D) of Diethanolamine (111-42-2) in B6C3F1 Mice Exposed via Topical Application
Pathology Tables
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Neoplastic
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Neoplastic
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
Genetic Toxicology Studies
Genetic Toxicity Evaluation of Diethanolamine (111-42-2) in Micronucleus Study A08796 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Diethanolamine in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 310797
Summary Data
- G06 - Ames Summary Data (128 KB)
Other NTP Studies
ADME/TK Evaluation (S0814) of Diethanolamine (111-42-2) in F344 Rats and B6C3F1 Mice Exposed via Gavage, Intravenous Injection or Topical Application
Prenatal Developmental Toxicity Study (TER96001) of Diethanolamine (111-42-2) in Sprague-Dawley Rats Exposed via Gavage
Individual and Summary Data
- Dam Data: Dam Body Weights (24 kB)
- Dam Data: Dam Feed Consumption (20 kB)
- Dam Data: Dam Pregnancy Status (3 kB)
- Dam Data: Dam Water Consumption (22 kB)
- Dam Data: Organ Weights (12 kB)
- Live Litter: Postnatal Data (114 kB)