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p-Nitrobenzoic acid (62-23-7)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID3020966


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
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  • No Evidence, Male, Rats
  • Some Evidence, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • No Evidence, Female, Mice
  • No Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to p-Nitrobenzoic acid (62-23-7).
Micronucleus - Mice
View
  • Male: Negative
    Female: Negative
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to p-Nitrobenzoic acid (62-23-7).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to p-Nitrobenzoic acid (62-23-7).
Bacterial Mutagenicity
View
  • Positive

Citation Information


NTP. p-Nitrobenzoic acid (62-23-7). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-442 Toxicology and Carcinogenesis Studies of p-Nitrobenzoic Acid (CASRN 62-23-7) in F344/N Rats and B6C3F1 Mice (Feed Studies)
Zeiger E, Anderson B, Haworth S, Lawlor T, Mortelmans K, Speck W. Salmonella mutagenicity tests: III. Results from the testing of 255 chemicals. Environ Mutagen. 1987;9 Suppl 9:1-109.
Witt, K.L., Knapton, A., Wehr, C.M., Hook, G.J., Mirsalis, J., Shelby, M.D., and MacGregor, J.T. Micronucleated Erythrocyte Frequency in Peripheral Blood of B6C3F1 Mice from Short-Term, Prechronic, and Chronic Studies of the NTP Carcinogenesis Bioassay Program. Environ. Molec. Mutagen. Vol. 36 (2000) 163-194
Zeiger, E., Shelby, M., Ivett J., and McFee, A. Mutagenicity testing of 5-(4-nitrophenyl)-2, 4-pentadien-1-al ("Spy Dust") and its metabolites in vitro and in vivo. Environ. Mutagen. Vol. 9 (1987) 269-280

Study Data


Toxicity and Carcinogenicity Studies


3-Month Evaluation of the Toxicity (C61778) of p-Nitrobenzoic Acid (62-23-7) in F344/N Rats Exposed via Dosed Feed
3-Month Evaluation of the Toxicity (C61778) of p-Nitrobenzoic Acid (62-23-7) in B6C3F1 Mice Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity (C61778B) of p-Nitrobenzoic Acid (62-23-7) in F344/N Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity (C61778B) of p-Nitrobenzoic Acid (62-23-7) in B6C3F1 Mice Exposed via Dosed Feed

Genetic Toxicology Studies


Genetic Toxicity Evaluation of p-Nitrobenzoic Acid (62-23-7) in Micronucleus Study A44876 in B6C3F1 Mice
Genetic Toxicity Evaluation of p-Nitrobenzoic Acid in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 699655
Summary Data