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Diazoaminobenzene (136-35-6)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID9024934


Study Results


Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to Diazoaminobenzene (136-35-6).
Micronucleus - Mice
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  • Male: Positive
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  • Male: Positive
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Diazoaminobenzene (136-35-6).
Bacterial Mutagenicity
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  • Positive

Citation Information


NTP. Diazoaminobenzene (136-35-6). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TOX-73 Metabolism, Toxicity, and Predicted Carcinogenicity Studies of Diazoaminobenzene Administered Dermally to F344/N Rats and B6C3F1
Zeiger E, Anderson B, Haworth S, Lawlor T, Mortelmans K, Speck W. Salmonella mutagenicity tests: III. Results from the testing of 255 chemicals. Environ Mutagen. 1987;9 Suppl 9:1-109.
Ress NB, Witt KL, Xu J, Haseman JK, Bucher JR. Micronucleus induction in mice exposed to diazoaminobenzene or its metabolites, benzene and aniline: implications for diazoaminobenzene carcinogenicity. Mutation Res. Vol. 521 (2002) 201 - 208

Study Data


Toxicity and Carcinogenicity Studies


16-Day Evaluation of the Toxicity (C96002) of Diazoaminobenzene (136-35-6) in F344 Rats Exposed via Topical Application. NTP Special Study
16-Day Evaluation of the Toxicity (C96002) of Diazoaminobenzene (136-35-6) in B6C3F1 Mice Exposed via Topical Application. NTP Special Study
2-Week Evaluation of the Toxicity (C96002) of Diazoaminobenzene (136-35-6) in F344/N Rats Exposed via Topical Application
2-Week Evaluation of the Toxicity (C96002) of Diazoaminobenzene (136-35-6) in B6C3F1 Mice Exposed via Topical Application

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Diazoaminobenzene (136-35-6) in Micronucleus Study A64807 in B6C3F1 Mice
Genetic Toxicity Evaluation of Diazoaminobenzene (136-35-6) in Micronucleus Study A72640 in B6C3F1 Mice
Genetic Toxicity Evaluation of Diazoaminobenzene in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 529702
Summary Data

Other NTP Studies


ADME/TK Evaluation (S0638) of Diazoaminobenzene (136-35-6) in F344/N Rats and B6C3F1 Mice Exposed via Gavage, Intravenous Injection or Topical Application