Substance Name	CASRN	MW (g/mol)	Physical Form	LLNA	Vehicle for LLNA Test	EC3	Number of LLNA Studies	0.5x - 2.0x EC3	Max SI (Conc)	GPMT/BT	HMT	HPTA	Peptide Reactivity	Additional Human Skin Sensitization Data/Information
CMI/MI	55965-84-9	149.599	Liquid	+	DMF	0.009	1	0.0045-0.018	22.7 (0.1%)	+		+	High	DSA05HRIPT=4.3 (Cardin et al. 1986) Human data is for mixture (Kathon CG) – no human data for single substance
Chlorobenzene	108-90-7	112.557	Liquid	-	AOO	NC	1	NA	1.7 (10%)	-			Minimal	No human data located
Cinnamic alcohol	104-54-1	134.18	Solid	+	AOO	21	1	10.5-42	5.7 (90%)	+	+			DSA05HRIPT=3704; DSA05HMT=625 (Jordan and King 1977)
Citral	5392-40-5	152.233	Liquid	+	AOO	9.2	6	4.6-18.3	20.5 (20%)	+	+			DSA05HRIPT=840; DSA05HMT=862 (Steltenkamp et al. 1980)
Cobalt chloride	7646-79-9	129.84	Solid	+	DMSO	0.6	2	0.3-1.2	7.2 (5%)	+	+	+		DSA05HMT=172 (Kligman 1966b) human data is for cobalt sulfate
"2,4-Dinitrochloro-benzene"	97-00-7	202.552	Solid	+	AOO	0.049	15	0.025-0.099	43.9 (0.025%)	+			High	DSA05HRIPT=5.5 (Friedmann et al. 1983)
Ethylene glycol dimethacrylate 	97-90-5	198.216	Liquid	+	MEK	28	1	14-56	7 (50%)	-		+	High	+ human from Basketter et al. 1999a
Eugenol	97-53-0	164.201	Liquid	+	AOO	10.1	11	5.05-20.2	17 (50%)	+		+		DSA05HRIPT=5926 (Marzulli and Maibach 1980)
Hexyl cinnamic aldehyde	101-86-0	216.319	Liquid	+	AOO	9.7	21	4.8-19.5	20 (50%)	+			Minimal	DSA(NOEL)HRIPT=23622 (RIFM submission and Basketter et al. 2005b)
Lactic acid	50-21-5	90.078	Liquid	-	DMSO	NC	1	NA	2.2 (25%)	-			Minimal	No human data located
Imidazolidinyl urea	39236-46-9	388.294	Solid	+	DMF	24	1	Dec-48	5.5 (50%)	+		+	Moderate	DSA05HRIPT=3846 (Jordan and King 1977)
Isoeugenol	97-54-1	164.201	Liquid	+	AOO	1.5	47	0.77-3.1	31 (5%)	+		+		DSA(LOEL) HRIPT=69 (Griem et al. 2003); DSA(LOEL)HMT=5217
Isopropanol	67-63-0	60.095	Liquid	-	AOO	NC	1	NA	1.7 (10%)	-			Minimal	Studies indicate substance produces skin sensitization
2-Mercaptobenzo-thiazole	149-30-4	167.253	Solid	+	DMF	1.7	1	0.85-3.4	8.6 (10%)	+	+	+	High	DSA05HMT=1642 (Kligman 1966a)
Methyl methacrylate	80-62-6	100.12	Liquid	+	AOO	90	1	45-100	3.6 (100%)	+				Information derived from clinical experience
Methyl salicylate	119-36-8	152.147	Liquid	-	AOO	NC	9	NA	2.7 (20%)	-	-	-	Minimal	DSA05HMT=5517 (Schneider and Akkan 2004)
Nickel chloride	7718-54-9	129.599	Solid	-	DMSO	NC	2	NA	2.4 (5%)	+				DSA05HMT=28 (Kligman 1966a for nickel sulfate – but data expressed as nickel)
Phenyl benzoate9	93-99-2	198.217	Solid	+	AOO	13.6	3	6.8-27.2	11.1 (25%)	+				DSA05HRIPT=52489 (Basketter et al. 2005b)
4-Phenylenediamine	106-50-3	108.14	Solid	+	AOO	0.11	6	0.055-0.22	26.4 (1%)	+	+	+		DSA05HMT=16.4 (Kligman 1966a); DSA05HRIPT=6.9 (Marzulli and Maibach 1974)
Salicylic acid	69-72-7	138.121	Solid	-	AOO	NC	1	NA	2.5 (25%)	-	-	-		DSA(NOEL) HMT=13793 (Kligman 1966b)
Sodium lauryl sulfate	151-21-3	288.38	Solid	+	DMF	8.1	5	4.05-16.2	8.9 (10%)	-	-	-		DSA(NOEL) HMT=6897 (Kligman 1966b)
Xylene	1330-20-7	106.17	Liquid	+	AOO	95.8	1	47.9-100	3.1 (100%)	NA16	-			DSA (NOEL)=68966 (Kligman 1966b)