Summaries & Associations of Study Results
| Levels of Evidence of Carcinogenicity | May Have Been Related | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TR | Chemical | Salmonella Results | Route | Male Rats | Female Rats | Male Mice | Female Mice | Sex/Species | Multiple Tumor Sites | |||
| TR-049 | Acronycine | Intraperitoneal Injection | (P) | (P) | IS | IS | Yes | |||||
| TR-452 | 2,2-bis(Bromomethyl)-1,3-propanediol | +,+,- | Dosed-Feed | (CE) | CE | CE | CE | Yes | ||||
| TR-467 | Chloroprene | - | Inhalation | CE | CE | CE | (CE) | Yes | ||||
| TR-207 | Cytembena | + | Intraperitoneal Injection | (P) | P | N | N | Yes | ||||
| TR-210 | 1,2-Dibromoethane | + | Inhalation | (P) | P | P | P | Yes | ||||
| TR-400 | 2,3-Dibromo-1-propanol | + | Topical Application | (CE) | CE | CE | CE | Yes | ||||
| TR-372 | 3,3'-Dimethoxybenzidine dihydrochloride | Dosed-Water | (CE) | CE | Yes | |||||||
| TR-390 | 3,3'-Dimethylbenzidine dihydrochloride | + | Dosed-Water | (CE) | CE | Yes | ||||||
| TR-152 | Ethyl tellurac | -,- | Dosed-Feed | (E) | N | E | E | Yes | ||||
| TR-374 | Glycidol | +,+ | Gavage | (CE) | CE | CE | CE | Yes | ||||
| TR-018 | IPD (3,3'-iminobis-1-propanol dimethanesulfonate (ester) hydrochloride) | Intraperitoneal Injection | (E) | (E) | E | E | Yes | |||||
| TR-491 | Methyleugenol | - | Gavage | (CE) | CE | CE | CE | Yes | ||||
| TR-337 | Nitrofurazone | + | Dosed-Feed | (EE) | CE | NE | CE | Yes | ||||
| TR-504 | o-Nitrotoluene | -,- | Dosed-Feed | (CE) | CE | CE | CE | Yes | ||||
| TR-483 | Pentachlorophenol, purified | Dosed-Feed | (SE) | NE | Yes | |||||||
| TR-072 | Phenoxybenzamine hydrochloride | + | Intraperitoneal Injection | (P) | (P) | (P) | (P) | No | ||||
| TR-153 | o-Toluidine hydrochloride | +,- | Dosed-Feed | (P) | P | P | P | Yes | ||||
| Totals | 16 | 3 | 1 | 2 | ||||||||
| The number of chemicals causing tumors in Mesothelium (Abdominal Cavity/Tunica Vaginalis) is 17. | ||||||||||||
Levels of Evidence of Carcinogenicity: CE or P = Clear Evidence, SE = Some Evidence, EE or E = Equivocal Evidence, NE or N = No Evidence, IS = Inadequate Experiment Salmonella Results: + = Positive, +W = Weakly Positive, ? = Inconclusive, - = Negative Parentheses indicate the animal group in which a tumor occurred in the organ specified. Sex/Species: MR = Male Rats, FR = Female Rats, MM = Male Mice, FM = Female Mice Totals include positive, equivocal and may-have-been-related responses where a tumor occurred in the organ specified. NOTE: Blank space under the animal groups indicates no experiments were done. | ||||||||||||
Web page last updated on May 14, 2008
