National Toxicology Program

National Toxicology Program

Perfluorohexanoic acid (PFHXA)

http://ntp.niehs.nih.gov/go/TS-M040048

CASRN: 307-24-4

Formula: C6-H-F11-O2

Synonyms/Common Names:

  • C6 CARBOXYLIC ACID
  • HEXANOIC ACID, UNDECAFLUORO-

Known Uses:

Breakdown product of stain- and grease-proof coatings on food packaging and household products.

Nomination Background

Short-Term Toxicity

  • 28 days (Gavage)  (C20613)  Completed 
    • Rats: Harlan Sprague-Dawley
    • Dose: M&F: 0, 31.3, 62.5, 125, 250, or 500 mg/kg/2x day.

Genetic Toxicology

  • Micronucleus  (G04048)  Completed 
    • Rats
    • Male Equivocal 
    • Female Negative 
  • Salmonella  (A97455)  Completed 
    •  Negative 

Organ Systems Toxicity

  • Selected (R04048)  
    The NTP is administratively located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.

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