National Toxicology Program

CASRN: 1239-45-8

Formula: C21-H20-N3.Br

Synonyms/Common Names:

• HOMODIUM BROMIDE
• PHENANTHRIDINIUM, 3,8-DIAMINO-5-ETHYL-6-PHENYL-, BROMIDE (8CI)(9CI)

Known Uses:

Reagent of DNA chemistry; DNA interchelating agent for biochemical & molecular biology research. Some reported use as an antiparasitic & antiprotazoic drug in animals; has also been used as a drug or drug precursor.

Nomination Background

Genetic Toxicology

• Micronucleus  (A59443)  Completed 
  • Rats: Fischer 344
  • Male Negative 
• Micronucleus  (A69208)  Completed 
  • Mice: B6C3F1
  • Male Negative 
• Salmonella  (A67248)  Completed 
  •  Positive