NICEATM is collaborating with the PETA International Science Consortium (PISC), the U.S. Environmental Protection Agency (EPA), and industry scientists to support a workgroup focused on inhalation toxicity. The workgroup met February 24-25, 2015, at EPA in Washington to define specifications for development and evaluation of an in vitro system to assess inhalation toxicity of multiwalled carbon nanotubes. Recommendations included designing a system that would include different lung cells co-cultured at an air-liquid interface and that would consider relevant human dosimetry and nanomaterial lifecycle transformations. These recommendations were central to a subsequent request for proposals issued by PISC for funding to develop an appropriate testing system; funding was awarded in September 2015.
This activity followed a NICEATM request for information (79 FR 35176, June 19, 2014) on devices and/or technologies currently used for identifying potential inhalation hazards.