The NTP Office of Health Assessment and Translation develops literature-based evaluations to reach conclusions about potential human health hazards and to examine the state of the science. In 2012, OHAT began implementing systematic review methodology to carry out these evaluations. The output from an evaluation can vary including, but not limited to: NTP Monograph, state of the science workshop report, or peer-reviewed journal publication. All evaluations follows a similar process with opportunities for external scientific, public, and interagency input.
The 7 steps of the Draft OHAT Approach for Systematic Review and Evidence Integration for Literature-based Health Assessments – February 2013 (Draft OHAT Approach – February 2013) are included in the OHAT Evaluation Process schematic.
The Draft OHAT Approach – February 2013 provides a framework for incorporating systematic review and evidence integration into OHAT literature-based health assessments and is discussed at http://ntp.niehs.nih.gov/go/38673.