The following is a list of substances that have been nominated to the RoC, but have not yet been approved for formal review. For information on selected substances currently under review, see Candidate Substances.
Family of products consisting of elemental carbon in the form of colloidal particles that rapidly form aggregates. The products are used primarily for rubber reinforcement, but are also used as black pigments and for electrical conductivity purposes.
A mixture of combustion products of diesel fuel; the exact composition of the mixture depends on the nature of the engine, operating conditions, lubricating oil, additives, emission control system, and fuel composition. Occupational exposure occurs primarily among miners (who use diesel power equipment), railroad workers and transportation workers such as truck drivers.
Currently listed as Reasonably Anticipated to be a Human Carcinogen in the 12th RoC
Indium compounds are chemicals that include the metal indium. Indium phosphide is used primarily in the semiconductor industry; however, most of the semiconductor industry in the U.S. is silicon based. Other indium compounds (such as indium tin oxide) are primarily used in optoelectronics and flat panel display technology.
Iron is a transition metal that exists mainly in the ferrous (2+) and ferric (3+) oxidation states in biological systems. It is used for medical treatment, as well as for other consumer and industrial needs. It is also found naturally in food. Iron overload disorders can be hereditary, acquired or iatrogenic.
Herbal remedy (botanical product) used as an alternative to anti-anxiety drugs or for hyperactivity in children, and as a skin-condition agent in cosmetics. Roots used in kava beverages, which have sedative and anesthetic properties.
Used in the manufacture of pharmaceuticals, photographic chemicals, dyes and pigments, cleaning and agricultural chemicals, and rubber. Also found in tobacco smoke and food and drinks containing caramel coloring.
Used in the manufacturing of fluoropolymers. Fluoropolymers are primarily used to provide non-stick to cookware and waterproof membranes for clothing. They are also used in other applications and have fire-resistance properties.
Depleted uranium (DU) is a byproduct of the production of enriched uranium for use in nuclear reactors. It has a lower content of the isotope U-235 and emits fewer alpha particles than natural uranium. Because of its high density, the military uses DU for armor-piercing munitions and armor plates. It has also been used as counterbalance weight in aircraft, and radiation shielding in medical radiation therapy.
Viruses (selected): Kaposi's sarcoma – associated herpesvirus, Epstein-Barr virus (EBV), human T-cell lymphotropic virus type 1 (HTLV-1), human immunodeficiency virus (HIV), and Merkel cell polyomavirus (MCV)
EBV and Kaposi's sarcoma - associated herpesvirus are members of the herpesvirus family, which are double stranded DNA viruses with a capsid, and cause characteristic lesions. EBV causes infectious mononucleosis.
HIV and HTLV-1 are retroviruses; HTLV-1 causes multiple disorders including an inflammatory neurological disease. HIV causes acquired immunodeficiency syndrome.
MCV is a non-enveloped, double-stranded DNA virus.
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