https://ntp.niehs.nih.gov/go/7156

Propyl gallate: Target Organs and Levels of Evidence for TR-240

Carcinogenesis Bioassay of Propyl Gallate (CASRN 121-79-9) in F344/N Rats and B6C3F1 Mice (Feed Study)

Chemical (Study Title)
CASRN		 Peer Review Date Route/Exposure Levels Study Laboratory
Propyl gallate
121-79-9		 12/16/1981 Dosed-Feed
0,6000,12000 PPM/50 PER GROUP		 Southern Research Institute

Levels of Evidence

Male Rats: Equivocal
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Preputial Gland: ADENOMA 0/50 5/50 0/50; ADENOMA, ADENOCARCINOMA 0/50 3/50 0/50, OR CARCINOMA 1/50 0/50 0/50 COMBINED 1/50 8/50 0/50
  • Pancreas Islet Cell: ADENOMA 0/50 8/50 2/50 ADENOMA OR CARCINOMA 2/50 1/50 2/50 COMBINED 2/50 9/50 4/50
  • Adrenal Gland Medulla: PHEOCHROMOCYTOMA 4/50 13/48 8/50
Female Rats: Negative
Male Mice: Equivocal
Type Organ/Tissue (Lesion)
Neoplastic Lesions
  • Hematopoietic System: LYMPHOMA 1/50 3/49 8/50
Female Mice: Negative