National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-c01581

beta-Thioguanidine deoxyriboside - C01581

CASRN: 789-61-7

Formula: C10-H13-N5-O3-S

Synonyms/Common Names:

  • 2'-DEOXY-6-THIOGUANOSINE (9CI)
  • BETA-TGDR

Known Uses:

Anticancer drug

Short-Term Toxicity

  • 14-Day (Intraperitoneal Injection)  (C01581)  Completed 
    • Rats: Sprague Dawley; Mice: B6C3F1
  • 13-Week (Intraperitoneal Injection)  (C01581)  Completed 
    • Rats: Sprague Dawley; Mice: B6C3F1

Long-Term Carcinogenicity

  • 2-Year (Intraperitoneal Injection)  (C01581)  Report Complete 
    • TR-057 (NIH Number: 78-1363; NTIS Number: PB281540)  (Peer Review Approval 02/18/1978A )
      Bioassay of �-TGdR for Possible Carcinogenicity (CASRN 789-61-7)
    • Rats: Sprague Dawley; Mice: B6C3F1
    • Carcinogenesis Results
      • Male Rats Equivocal 
      • Female Rats Positive 
      • Male Mice Inadequate Study 
      • Female Mice Inadequate Study 
The NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.