National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-m940107

Ethidium bromide - M940107

 

CASRN: 1239-45-8

Formula: C21-H20-N3.Br

Synonyms/Common Names

  • Homodium bromide
  • Phenanthridinium, 3,8-diamino-5-ethyl-6-phenyl-, bromide (8CI)(9CI)

Known Uses

Reagent of DNA chemistry; DNA interchelating agent for biochemical & molecular biology research. Some reported use as an antiparasitic & antiprotazoic drug in animals; has also been used as a drug or drug precursor.

Chemical Properties

Toxicity Effects (HSDB)

Nomination Background

Genetic Toxicology

  • Micronucleus  (A59443)  Completed 
    • Rats: Fischer 344
    • Male Negative 
  • Micronucleus  (A69208)  Completed 
    • Mice: B6C3F1
    • Male Negative 
  • Salmonella  (A67248)  Completed 
    •  Positive 
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.