National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-m990056

Aloe vera gel - M990056

CASRN: 8001-97-6

Known Uses:

Aloe gel is used in health-oriented drinks, cosmetics and personal care products. Used to promote rapid healing of burns, dermal ulcers & wounds and to impede bacterial growth on the skin.

Nomination Background

Long-Term Carcinogenicity

  • 40 weeks (Topical Application)  (C20116C)  Report Complete 
    • TR-553 (NIH Number: 10-5894; NTIS Number: PB2011-101386)  (Peer Review Approval 02/27/2008A )
      Photococarcinogenesis Study of Aloe Vera [CASRN 481-72-1 (Aloe-emodin)] in SKH-1 Mice (Simulated Solar Light and Topical Application Study)
    • Mice: SKH-1 Hairless
    • Dose: 0, 3%, OR 6% COMPOUND WITH SIMULATED LIGHT EXPOSURES.

Genetic Toxicology

  • Salmonella  (A20251)  Completed 
    •  Negative 
  • Salmonella  (G99056)  Completed 
    •  Negative 
The NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.