Developmental (Teratology) Abstracts
The following list of abstracts represents studies conducted by NTP. Studies conducted before 1985 have not been included in the list. These studies have not been evaluated by the levels of evidence criteria for reproductive or developmental toxicity established by NTP in March 2009. Because this is not a comprehensive list, email us or use our contact form to inquire about other studies.
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| Abstract | Substance/Topic | Report Title | Year | Type | Alphabetical |
|---|---|---|---|---|---|
| Filter by Letter: | Filter by Year: | Filter by Type: | |||
| TER87036 | Acetone | Inhalation Developmental Toxicology Studies: Teratology Studies of Acetone (CASRN: 67-64-1) in Swiss (CD-1) Mice and Sprague Dawley Rats | 1988 | Developmental | A |
| TER87140 | Acetone | Inhalation Developmental Toxicology Studies: Teratology Studies of Acetone (CASRN: 67-64-1) in Swiss (CD-1) Mice and Sprague Dawley Rats | 1988 | Developmental | A |
| TER91039 | Acetonitrile | Inhalation Development Toxicology Studies: Acetonitrile (CASRN: 75-05-8) in Sprague Dawley Rats | 1994 | Developmental | A |
| TER88048 | Acrylamide | Teratologic Evaluation of Acrylamide (CASRN: 791-06-1) Administered to Sprague Dawley (CD) Rats on Gestational Days 6 Through 20 | 1988 | Developmental | A |
| TER89049 | Acrylamide | Teratologic Evaluation of Acrylamide (CASRN: 79-06-1) Administered to CD-1 (Swiss Mice) on Gestational Days 6 Through 17 | 1988 | Developmental | A |
| TER87038 | Arsine | Arsine (CASRN: 7784-42-1): Absence of Developmental Toxicity in Rats and Mice | N/A | Developmental | A |
| RACB98001 | 3'-Azido-3'-deoxythymidine (AZT) | Developmental Toxicity Evaluation of 3'-Azido-3'-deoxythymidine (AZT) (CASRN: 30516-87-1) and Dapsone (CASRN: 80-08-0) Administered by Gavage to Swiss Albino (CD-1) Mice on Gestational Days 6 Through 15 | 2004 | Developmental | A |
| TER97001 | 3'-Azido-3'-deoxythymidine (AZT) | Developmental Toxicity Evaluation of 3'-Azido-3'-deoxythymidine (AZT) (CASRN: 30516-87-1) and 2', 3'-Dideoxycytidine (ddC) (CASRN: 7481-89-2) Administered by Gavage to Swiss Albino (CD-1) Mice on Gestational Days 6-15 | 2002 | Developmental | A |
| TER20203 | 3'-Azido-3'-deoxythymidine (AZT) | Developmental Toxicity Evaluation of 3'-Azido-3'-deoxythymidine (AZT) (CASRN: 30516-87-1) and (-) 2', 3'-Dideoxy-3'-thiacytidine (3TC) (CASRN: 134678-17-4) Co-administered by Gavage to Swiss Albino (CD-1) Mice on Gestational Days 6 Through 16 | 2004 | Developmental | A |
| TER84050 | Bendectin | Teratologic Evaluation of Bendectin (CASRN: 8064-77-5), in Sprague Dawley (CD) Rats | 1984 | Developmental | B |
| TER98005 | Benzophenone | Developmental Toxicity Evaluation for Benzophenone (CASRN: 119-61-9) Administered by Gavage to Sprague Dawley (CD) Rats on Gestational Days 6 Through 19 | 2002 | Developmental | B |
| TER99001 | Benzophenone | Developmental Toxicity Evaluation for Benzophenone (CASRN: 119-61-9) Administered by Gavage to New Zealand White Rabbits on Gestational Days 6 Through 29 | 2004 | Developmental | B |
| TER20102 | Berberine Chloride Dihydrate | Developmental Toxicity Research Evaluation for Berberine Chloride Dihydrate (CASRN: 5956-60-5) Administered by Gavage to Sprague Dawley (CD) Rats on Gestational Days 6 Through 19 | 2002 | Developmental | B |
| TER20103 | Berberine Chloride Dihydrate | Developmental Toxicity Research Evaluation for Berberine Chloride Dihydrate (CASRN: 5956-60-5) Administered by Gavage to Swiss (CD-1) Mice on Gestational Days 6 Through 16 | 2003 | Developmental | B |
| TER98008 | Berberine Chloride Dihydrate | Developmental Toxicity Evaluation for Berberine Chloride Dihydrate (CASRN: 5956-60-5) Administered in the Feed to Sprague Dawley (CD) Rats on Gestational Days 6 to 20 | 2003 | Developmental | B |
| TER99002 | Berberine Chloride Dihydrate | Developmental Toxicity Evaluation of Berberine Chloride Dihydrate (CASRN: 5956-60-5) Administered in the Feed to Swiss (CD-1) Mice on Gestational Days 6 to 17 | 2003 | Developmental | B |
| TER85051 | Bisphenol A | Teratologic Evaluation of Bisphenol A (CASRN: 80-05-7) Administered to CD Rats on Gestational Days 6 Through 15 | 1985 | Developmental | B |
| TER85052 | Bisphenol A | Teratologic Evaluation of Bisphenol A (CASRN: 80-05-7), in CD-1 Mice on Gestational Days 6 Through 15 | 1985 | Developmental | B |
| TER89027 | Boric Acid | Developmental Toxicity of Boric Acid (CASRN: 10043-35-3) Administered in Feed to Sprague Dawley (CD) Rats on Gestational Days 0 to 20 or 6 to 15 | 1990 | Developmental | B |
| TER89028 | Boric Acid | Developmental Toxicity Evaluation of Boric Acid (CASRN: 10043-35-3) Administered in Feed to CD-1 Swiss Mice on Gestational Days 0 to 17 | 1989 | Developmental | B |
| TER90003 | Boric Acid | Developmental Toxicity Evaluation of Boric Acid (CASRN: 10043-35-3) Administered to New Zealand White Rabbits by Gavage on Gestational Days 6 Through 19 | 1991 | Developmental | B |
| TER90123 | Boric Acid | Evaluation of CNS Development in Sprague Dawley CD Rats Exposed to Boric Acid (CASRN: 10043-35-3) in Feed on Gestational Days 14-17 | 1994 | Developmental | B |
| TER93138 | Boric Acid | CNS Developmental Toxicity of Boric Acid (CASRN: 10043-35-3) in Sprague Dawley CD Rats Exposed on Gestation Days 6-15 | 1994 | Developmental | B |
| TER85144 | 1,3-Butadiene | Inhalation Developmental Toxicology Studies: Teratology Study of 1,3-Butadiene (CASRN: 106-99-0) in CD-1 Mice | 1987 | Developmental | B |
| TER89041 | 1,3-Butadiene | Inhalation Developmental Toxicology Studies of 1,3-Butadiene (CASRN: 106-99-0) in Sprague Dawley Rats | 1987 | Developmental | B |
| TER90030 | 1,4-Butanediol | Inhalation Developmental Toxicology Studies: Teratology Study of 1,4-Butanediol (CASRN: 110-63-4), in Swiss (CD-1) Mice | 1994 | Developmental | B |
| TER97004 | 1,2,3,4-Butanetetracarboxylic Acid | Developmental Toxicity Evaluation for 1,2,3,4-Butanetetracarboxylic Acid (CASRN: 1703-58-8) Administered by Gavage to Sprague Dawley (CD) Rats from Gestational Day 6 Through 19 | 1999 | Developmental | B |
| TER88025 | Butyl Benzyl Phthalate | Developmental Toxicity of Butyl Benzyl Phthalate (CASRN: 85-68-7) Administered in Feed to CD Rats on Gestational Days 6 to 15 | 1989 | Developmental | B |
| TER89026 | Butyl Benzyl Phthalate | Developmental Toxicity of Butyl benzyl phthalate (CASRN: 85-68-7) in CD-1 Swiss Mice | 1990 | Developmental | B |
| TER91018 | d-Camphor | Developmental Toxicity of d-Camphor (CASRN: 464-49-3) in Sprague Dawley (CD) Rats | 1992 | Developmental | C |
| TER91019 | d-Camphor | Developmental Toxicity of d-Camphor (CASRN: 464-49-3) in New Zealand White (NZW) Rabbits | 1992 | Developmental | C |
| TER84053 | Carbon Disulfide | Teratologic Evaluation of Carbon Disulfide (CASRN: 75-15-0) Administered to CD Rats on Gestational Days 6 Through 15 | 1984 | Developmental | C |
| TER84054 | Carbon Disulfide | Teratologic Evaluation of Carbon Disulfide (CASRN: 75-15-0) Administered to New Zealand White Rabbits on Gestational Days 6 Through 19 | 1984 | Developmental | C |
| TER91042 | Chloroprene | Inhalation Developmental Toxicology Studies: Developmental Toxicity of Chloroprene (CASRN: 126-99-8) Vapors in New Zealand White Rabbits | 1994 | Developmental | C |
| TER82055 | Chlorpromazine Hydrochloride | Chlorpromazine Hydrochloride (CASRN: 69-09-0) Administered to Fischer/344 Rats on Gestational Days 6 Through 15 | 1983 | Developmental | C |
| TER82056 | Chlorpromazine Hydrochloride | Chlorpromazine Hydrochloride (CASRN: 69-09-0) Administered to CD-1 Mice on Gestational Days 6 Through 15 | 1983 | Developmental | C |
| TER90057 | Codeine | Codeine (CASRN: 76-57-3) Administered to CD-1 Mice on Gestational Days 6 Through 15 | 1987 | Developmental | C |
| TER90058 | Codeine | Codeine (CASRN: 76-57-3) in LVG Hamsters on Gestational Days 5 Through 13 | 1987 | Developmental | C |
| TER87118 | Corn Oil | Teratologic Evaluation of Corn Oil (CASRN: 8001-30-7) or Distilled Water Administered to CD Rats on Gestational Days 6 Through 15 | 1989 | Developmental | C |
| TER87119 | Corn Oil | Teratologic Evaluation of Corn Oil (CASRN: 8001-30-7) and Distilled Water Administered by Gavage to CD-1 Mice on Gestational Days 6 Through 15 | 1988 | Developmental | C |
| TER92135 | a-Cyclodextrin | Developmental Toxicity of a-Cyclodextrin (CASRN: 10016-20-3) in Swiss (CD-1) Mice (CASRN: 10016-20-3) | 1994 | Developmental | C |
| TER92136 | a-Cyclodextrin | Developmental Toxicity of a-Cyclodextrin (CASRN: 10016-20-3) in Sprague Dawley CD Rats | 1994 | Developmental | C |
| RACB98001 | Dapsone | Developmental Toxicity Evaluation of 3'-Azido-3'-deoxythymidine (AZT) (CASRN: 30516-87-1) and Dapsone (CASRN: 80-08-0) Administered by Gavage to Swiss Albino (CD-1) Mice on Gestational Days 6 Through 15 | 2004 | Developmental | D |
| ORST800001 | 2,4-Dichiorophenoxyacetic Acid | Evaluation of 2,4-dichiorophenoxyacetic acid (2,4-D), 2,4,5-trichlorophenoxyacetic acid (2,4,5-T), and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) toxicity in C57BL/6 mice: Reproduction and Fertility in Treated Male Mice and Evaluation of Congenital Malformations in Their Offspring (CASRN: AGNTORANGEMX) | 1980 | Developmental | D |
| TER20201 | 2',3'-Didehydro-3'-Deoxythymidine | Developmental Toxicity Evaluation of 2',3'-Dideoxyinosine (CASRN: 69655-05-6) and 2',3'-Didehydro-3'-Deoxythymidine (CASRN: 3056-17-5) Co-administered by Gavage to Swiss Albino (CD-1) Mice on Gestational Days 6 Through 16 | 2004 | Developmental | D |
| TER97001 | 2',3'-Dideoxycytidine (ddC) | Developmental Toxicity Evaluation of 3'-Azido-3'-deoxythymidine (AZT) (CASRN: 30516-87-1) and 2', 3'-Dideoxycytidine (ddC) (CASRN: 7481-89-2) Administered by Gavage to Swiss Albino (CD-1) Mice on Gestational Days 6-15 | 2002 | Developmental | D |
| TER20201 | 2',3'-Dideoxyinosine | Developmental Toxicity Evaluation of 2',3'-Dideoxyinosine (CASRN: 69655-05-6) and 2',3'-Didehydro-3'-Deoxythymidine (CASRN: 3056-17-5) Co-administered by Gavage to Swiss Albino (CD-1) Mice on Gestational Days 6 Through 16 | 2004 | Developmental | D |
| TER20203 | (-) 2',3'-Dideoxy-3'-thiacytidine (3TC) | Developmental Toxicity Evaluation of 3'-Azido-3'-deoxythymidine (AZT) (CASRN: 30516-87-1) and (-) 2', 3'-Dideoxy-3'-thiacytidine (3TC) (CASRN: 134678-17-4) Co-administered by Gavage to Swiss Albino (CD-1) Mice on Gestational Days 6 Through 16 | 2004 | Developmental | D |
| TER96001 | Diethanolamine | Developmental Toxicity Screen for Diethanolamine (CASRN: 111-42-2) Administered by Gavage to Sprague Dawley (CD) Rats on Gestational Days 6 Through 19: Evaluation of Dams and Pups Through Postnatal Day 21 | 1999 | Developmental | D |
| TER88065 | Diethyl Phthalate | Developmental Toxicity of Diethyl phthalate (CASRN: 84-66-2) Administered to CD Rats on Gestational Days 6 Through 15 | 1988 | Developmental | D |
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