Alimentary System

Stomach, Forestomach - Necrosis

    Narrative
    Stomach, Forestomach - Necrosis in a female B6C3F1 mouse from a chronic study. There is loss of cellular detail indicative of necrosis (arrow).
    Stomach, Forestomach - Necrosis in a female B6C3F1 mouse from a chronic study. There is loss of cellular detail indicative of necrosis (arrow).
    Stomach, Forestomach - Necrosis in a female B6C3F1 mouse from a chronic study (higher magnification of Figure 1). There is loss of cellular detail indicative of necrosis (arrow).
    Stomach, Forestomach - Necrosis in a female B6C3F1 mouse from a chronic study (higher magnification of Figure 1). There is loss of cellular detail indicative of necrosis (arrow).
    Stomach, Forestomach - Necrosis in a male F344 rat from a chronic study. There is loss of cellular detail and nuclei indicative of necrosis (arrow).
    Stomach, Forestomach - Necrosis in a male F344 rat from a chronic study. There is loss of cellular detail and nuclei indicative of necrosis (arrow).
    Stomach, Forestomach - Necrosis in a male F344 rat from a chronic study (higher magnification of Figure 3). There is loss of cellular detail and nuclei indicative of necrosis (arrow).
    Stomach, Forestomach - Necrosis in a male F344 rat from a chronic study (higher magnification of Figure 3). There is loss of cellular detail and nuclei indicative of necrosis (arrow).

    Authors:

    Linda H. Kooistra, DVM, PhD, DACVP
    Pathologist
    Charles River Laboratories, Inc.
    Research Triangle Park, NC

    Abraham Nyska, DVM, Diplomate ECVP, Fellow IATP
    Expert in Toxicologic Pathology
    Visiting Full Professor of Pathology
    Sackler School of Medicine, Tel Aviv University Timrat Israel

    Reviewers:

    Joel R. Leininger, DVM, PhD
    Senior Pathologist
    MedImmune
    Washington, DC

    Amy Brix, DVM, PhD, DACVP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC