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SACATM: Background Materials

September 2012

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Background Materials

News Articles – July 2011 to July 2012 

NTP Newsletter Updates on NICEATM-­‐ICCVAM – July 2011 to July 2012 

ALTEX Updates – July 2012 to July 2011 

2012 Society of Toxicology Annual Meeting Abstracts and Posters 

8th World Congress on Alternatives and Animal Use in the Life Sciences Proceedings and Abstracts (Montréal, Canada -­ August 21 -­ 25, 2011)

Using Fewer Animals to Identify Chemical Eye Hazards: Revised Criteria Necessary to Maintain Equivalent Hazard Classification

Regulatory Acceptance and Availability of ICCVAM-Recommended Alternative Test Methods

BG1Luc Estrogen Receptor Transcriptional Activation Test Method: Agonist and Antagonist Protocols

Use of the Murine Local Lymph Node Assay for Potency Categorization

New and Revised OECD Test Guidelines Based on ICCVAM Recommendations

Additional Information

High Throughput Screening (HTS) Adaptation and Performance of the BG1Luc ER TA Agonist and Antagonist Assays

Background Materials

ICCVAM Test Method Nomination

Electrophilic Contact Allergen Identification Screening Assay

Federal Agency Research, Development, Translation, and Validation Activities Relevant to the NICEATM-­‐ICCVAM Five-­‐Year Plan

NIH-­‐Led Programs and Collaborations (NIH, NCATS, FDA, and DARPA) Developing Alternative Test Methods


Update on EDSP21 Activities at EPA

DRAFT NICEATM-­‐ICCVAM Five-­‐Year Plan (2013-­‐2017)

Background Materials

International Workshops on Alternative Methods for Vaccine Testing

Report on the International Workshop on Alternative Methods for Human and Veterinary Rabies Vaccine Testing: State of the Science and Planning the Way Forward (Complete meeting materials available at:

International Workshop on Alternative Methods for Leptospira Vaccine Potency Testing: State of the Science and the Way Forward, September 19-­‐21, U.S. Department of Agriculture Center for Veterinary Biologics National Centers for Animal Health, Ames, Iowa 

International Workshop on Alternatives to the Murine Histamine Sensitization Test (HIST) for Acellular Pertussis Vaccines: State of the Science and the Path Forward, November 28-­‐ 29, 2012, William H. Natcher Center, National Institutes of Health, Bethesda, Maryland 

Contract Concept: NICEATM Support Contract 

Draft Report from the SACATM Implementation Working Group