NTP Logo

Annual Report for Fiscal Year 2015

Annual Report for Fiscal Year 2015
Menu
https://ntp.niehs.nih.gov/go/791112

Newly Reviewed Listings in the 13th RoC

Candidate Substance
CASRN*
Study Scientist
Primary Uses/Exposures Listing Status and Rationale
1-Bromopropane
106-94-5
Spencer
Halogenated alkane used as a solvent for cleaning or adhesives in a variety of industrial sectors including:
  • Spray adhesives
  • Vapor degreasing
  • Aerosol solvents
  • Dry-cleaning
People are primarily exposed to 1-bromopropane by inhalation or through the skin in workplaces that use or produce 1-bromopropane. 
Reasonably anticipated to be a human carcinogen.

Sufficient evidence of carcinogenicity from studies in experimental animals.
Cumene
98-82-8
Jahnke
Alkylated benzene found in fossil fuels and used primarily to produce phenol and acetone.

People are exposed to cumene in workplaces that produce or use cumene, or in gasoline transport related jobs. In their everyday lives, people can be exposed from breathing contaminated air or cigarette smoke.
Reasonably anticipated to be a human carcinogen.

Sufficient evidence of carcinogenicity from studies in experimental animals.
Pentachlorophenol and byproducts of its synthesis
87-86-5
Jahnke
Complex mixture primarily used as wood preservatives in the U.S.

People are exposed to the mixture in workplaces that treat wood, use treated wood, or in the past have produced it.

In their everyday lives, people can be exposed by breathing contaminated outdoor air, indoor air, and indoor dust; from the soil; and by ingesting water or food.
Reasonably anticipated to be a human carcinogen.

Limited evidence of carcinogenicity from studies in humans (non-Hodgkin lymphoma).
Sufficient evidence of carcinogenicity from studies in experimental animals.
ortho-Toluidine
95-53-4
Lunn
Arylamine used as an intermediate to manufacture herbicides, dyes, pigments, and rubber chemicals.

The highest exposure to ortho-toluidine occurs to people using it in the workplace. People are exposed to lower levels in their everyday lives from consumer products, medical products, cigarette smoke, and possibly the environment.
Known to be a human carcinogen.

Sufficient evidence of carcinogenicity from studies in humans.

* Chemical Abstracts Service Registry Number

Additional Links for the RoC