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Annual Report for Fiscal Year 2015

Annual Report for Fiscal Year 2015


NTP Reports and Documents

National Toxicology Program. 2015. Handbook for Conducting a Literature-Based Health Assessment Using Office of Health Assessment and Translation (OHAT) Approach for Systematic Review and Evidence Integration. Research Triangle Park, NC: National Toxicology Program. http://ntp.niehs.nih.gov/ntp/ohat/pubs/handbookjan2015_508.pdf

National Toxicology Program. 2015. Handbook for Preparing Report on Carcinogens Monographs. Research Triangle Park, NC: National Toxicology Program. http://ntp.niehs.nih.gov/ntp/roc/handbook/roc_handbook_508.pdf

National Toxicology Program. 2015. National Toxicology Program Monograph On Identifying Research Needs For Assessing Safe Use Of High Intakes Of Folic Acid. Research Triangle Park, NC: National Toxicology Program. http://ntp.niehs.nih.gov/ntp/ohat/folicacid/final_monograph_508.pdf

National Toxicology Program. 2015. National Toxicology Program Technical Report on the Toxicology and Carcinogenesis Studies of CIMSTAR® 3800 (CASRN CIMSTAR3800) in Wistar Han Rats and B6C3F1 Mice (Inhalation Studies). TR 586. Research Triangle Park, NC: National Toxicology Program. http://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr586_508.pdf

National Toxicology Program. 2014. National Toxicology Program Technical Report on the Toxicology Studies of Cobalt Metal (CASRN 7440-48-4) in F344/N Rats and B6C3F1/N Mice and Toxicology and Carcinogenesis Studies of Cobalt Metal in F344/NTac Rats and B6C3F1/N Mice (Inhalation Studies). TR 581. Research Triangle Park, NC: National Toxicology Program. http://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr581_508.pdf

National Toxicology Program. 2014. National Toxicology Program Technical Report on the Toxicology and Carcinogenesis Studies of Glycidamide (CASRN 5694-00-8) in F344/N Nctr Rats and B6C3F1/Nctr Mice (Drinking Water Studies). TR-588. Research Triangle Park, NC: National Toxicology Program. http://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr588_508.pdf

National Toxicology Program. 2015. National Toxicology Program Technical Report on the Toxicology and Carcinogenesis Studies of Vinylidene Chloride (CASRN 75-35-4) in F344/N Rats and B6C3F1 Mice (Inhalation Studies). TR 582. Research Triangle Park, NC: National Toxicology Program. http://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr582_508.pdf

National Toxicology Program. 2014. Report on Carcinogens, Thirteenth Edition. Research Triangle Park, NC: U.S. Department of Health and Human Services, Public Health Service.  http://ntp.niehs.nih.gov/pubhealth/roc/roc13/

Journal Articles and Book Chapters

Abdo N, Xia M, Brown CC, Kosyk O, Huang R, Sakamuru S, Zhou YH, Jack JR, Gallins P, Xia K, Li Y, Chiu WA, Motsinger-Reif AA, Austin CP, Tice RR, Rusyn I, Wright FA. 2015. Population-based in vitro hazard and concentration-response assessment of chemicals: the 1000 genomes high-throughput screening study. Environ Health Perspect 123:458-466. http://dx.doi.org/10.1289/ehp.1408775. [5]

Adler M, Ramm S, Hafner M, Muhlich JL, Gottwald EM, Weber E, Jaklic A, Ajay AK, Svoboda D, Auerbach S, Kelly EJ, Himmelfarb J, Vaidya VS. 2015. A quantitative approach to screen for nephrotoxic compounds in vitro. J Am Soc Nephrol. http://dx.doi.org/10.1681/asn.2015010060. [5]

Afanou KA, Straumfors A, Skogstad A, Nilsen T, Synnes O, Skaar I, Hjeljord L, Tronsmo A, Green BJ, Eduard W. 2014. Submicronic fungal bioaerosols: high-resolution microscopic characterization and quantification. Appl Environ Microbiol 80:7122-7130. http://dx.doi.org/10.1128/aem.01740-14. [2]

Afanou KA, Straumfors A, Skogstad A, Nayak AP, Skaar I, Hjeljord L, Tronsmo A, Eduard W, Green BJ. 2015. Indirect immunodetection of fungal fragments by field emission scanning electron microscopy. Appl Environ Microbiol 81:5794-5803. http://dx.doi.org/10.1128/aem.00929-15. [2]

Afanou KA, Straumfors A, Skogstad A, Skaar I, Hjeljord L, Skare O, Green BJ, Tronsmo A, Eduard W. 2015. Profile and morphology of fungal aerosols characterized by field emission scanning electron microscopy (FESEM). Aerosol Sci Technol 49:423-435. http://dx.doi.org/10.1080/02786826.2015.1040486. [2]

Ali S, Rosas-Hernandez H, Cuevas E, Lantz-McPeak S, Paule M, Gonzalez C, Rice K, Gannon B, Fantegrossi W. 2015. Methamphetamine, MDMA and bath salts induce cytotoxic effects in bovine brain microvessel endothelial cells. J Neurochem 134:220-220. http://dx.doi.org/10.1111/jnc.13188. [4]

Alves VM, Muratov E, Fourches D, Strickland J, Kleinstreuer N, Andrade CH, Tropsha A. 2015. Predicting chemically-induced skin reactions. Part I: QSAR models of skin sensitization and their application to identify potentially hazardous compounds. Toxicol Appl Pharmacol 284:262-272. http://dx.doi.org/10.1016/j.taap.2014.12.014. [5]

Alves VM, Muratov E, Fourches D, Strickland J, Kleinstreuer N, Andrade CH, Tropsha A. 2015. Predicting chemically-induced skin reactions. Part II: QSAR models of skin permeability and the relationships between skin permeability and skin sensitization. Toxicol Appl Pharmacol 284:273-280. http://dx.doi.org/10.1016/j.taap.2014.12.013. [5]

Andrade JE, Ju YH, Baker C, Doerge DR, Helferich WG. 2015. Long-term exposure to dietary sources of genistein induces estrogen-independence in the human breast cancer (MCF-7) xenograft model. Mol Nutr Food Res 59:413-423. http://dx.doi.org/10.1002/mnfr.201300780. [4]

Andrews RN, Keane M, Hanley KW, Feng HA, Ashley K. 2015. Manganese speciation of laboratory-generated welding fumes. Analytical Methods 7:6403-6410. http://dx.doi.org/10.1039/c5ay01147g. [1]

Armstrong JL, Day GA, Park JY, Stefaniak AB, Stanton ML, Deubner DC, Kent MS, Schuler CR, Virji MA. 2014. Migration of beryllium via multiple exposure pathways among work processes in four different facilities. J Occup Env Hyg 11:781-792. http://dx.doi.org/10.1080/15459624.2014.919392. [2]

Attene-Ramos MS, Huang R, Michael S, Witt KL, Richard A, Tice RR, Simeonov A, Austin CP, Xia M. 2015. Profiling of the Tox21 chemical collection for mitochondrial function to identify compounds that acutely decrease mitochondrial membrane potential. Environ Health Perspect 123:49-56. http://dx.doi.org/10.1289/ehp.1408642. [5]

Auerbach SS, Phadke DP, Mav D, Holmgren S, Gao Y, Xie B, Shin JH, Shah RR, Merrick BA, Tice RR. 2015. RNA-Seq-based toxicogenomic assessment of fresh frozen and formalin-fixed tissues yields similar mechanistic insights. J Appl Toxicol 35:766-780. http://dx.doi.org/10.1002/jat.3068. [5]

Awada R, Saulnier-Blache JS, Gres S, Bourdon E, Rondeau P, Parimisetty A, Orihuela R, Harry GJ, d'Hellencourt CL. 2014. Autotaxin downregulates LPS-induced microglia activation and pro-inflammatory cytokines production. J Cell Biochem 15:2123-2132. http://dx.doi.org/10.1002/jcb.24889. [5]

Badding MA, Schwegler-Berry D, Park JH, Fix NR, Cummings KJ, Leonard SS. 2015. Sintered indium-tin oxide particles induce pro-inflammatory responses in vitro, in part through inflammasome activation. PLoS One 10. http://dx.doi.org/10.1371/journal.pone.0124368. [2]

Bailey KA, Smith AH, Tokar EJ, Graziano JH, Kim KW, Navasumrit P, Ruchirawat M, Thiantanawat A, Suk WA, Fry RC. 2015. Mechanisms underlying latent disease risk associated with early-life arsenic exposure: Current research trends and scientific gaps. Environ Health Perspect. http://dx.doi.org/10.1289/ehp.1409360. [5]

Bal-Price A, Crofton KM, Sachana M, Shafer TJ, Behl M, Forsby A, Hargreaves A, Landesmann B, Lein PJ, Louisse J, Monnet-Tschudi F, Paini A, Rolaki A, Schrattenholz A, Sunol C, van Thriel C, Whelan M, Fritsche E. 2015. Putative adverse outcome pathways relevant to neurotoxicity. Crit Rev Toxicol 45:83-91. http://dx.doi.org/10.3109/10408444.2014.981331. [5]

Beery L, Harris JR, Collins JW, Current RS, Amendola AA, Meyers AR, Wurzelbacher SJ, Lampl M, Bertke SJ. 2014. Occupational injuries in Ohio wood product manufacturing: A descriptive analysis with emphasis on saw-related injuries and associated causes. Am J Ind Med 57:1265-1275. http://dx.doi.org/10.1002/ajim.22360. [2]

Beggs PJ, Katelaris CH, Medek D, Johnston FH, Burton PK, Campbell B, Jaggard AK, Vicendese D, Bowman DM, Godwin I, Huete AR, Erbas B, Green BJ, Newnham RM, Newbigin E, Haberle SG, Davies JM. 2015. Differences in grass pollen allergen exposure across Australia. Aust N Z J Public Health 39:51-55. http://dx.doi.org/10.1111/1753-6405.12325. [2]

Behl M, Hsieh JH, Shafer TJ, Mundy WR, Rice JR, Boyd WA, Freedman JH, Hunter ES, 3rd, Jarema K, Padilla S, Tice RR. 2015. Use of alternative assays to identify and prioritize organophosphorus flame retardants for potential developmental and neurotoxicity. Neurotoxicol Teratol. http://dx.doi.org/10.1016/j.ntt.2015.09.003. [5]

Behl M, Stout MD, Herbert RA, Dill JA, Baker GL, Hayden BK, Roycroft JH, Bucher JR, Hooth MJ. 2015. Comparative toxicity and carcinogenicity of soluble and insoluble cobalt compounds. Toxicology 333:195-205. http://dx.doi.org/10.1016/j.tox.2015.04.008. [5]

Beland FA, Olson GR, Mendoza MC, Marques MM, Doerge DR. 2015. Carcinogenicity of glycidamide in B6C3F mice and F344/N rats from a two-year drinking water exposure. Food Chem Toxicol. http://dx.doi.org/10.1016/j.fct.2015.09.017. [3]

Beverly BE, Lambright CS, Furr JR, Sampson H, Wilson VS, McIntyre BS, Foster PM, Travlos G, Gray LE, Jr. 2014. Simvastatin and dipentyl phthalate lower ex vivo testicular testosterone production and exhibit additive effects on testicular testosterone and gene expression via distinct mechanistic pathways in the fetal rat. Toxicol Sci 141:524-537. http://dx.doi.org/10.1093/toxsci/kfu149. [6]

Bhusari S, Pandiri AR, Nagai H, Wang Y, Foley J, Hong HL, Ton TV, DeVito M, Shockley KR, Peddada SD, Gerrish KE, Malarkey DE, Hooth MJ, Sills RC, Hoenerhoff MJ. 2015. Genomic profiling reveals unique molecular alterations in hepatoblastomas and adjacent hepatocellular carcinomas in B6C3F1 mice. Toxicol Pathol. http://dx.doi.org/10.1177/0192623315599853. [5]

Blackshear PE, Pandiri AR, Nagai H, Bhusari S, Hong HH, Ton TV, Clayton NP, Wyde M, Shockley KR, Peddada SD, Gerrish KE, Sills RC, Hoenerhoff MJ. 2015. Gene expression of mesothelioma in vinylidene chloride-exposed F344/N rats reveal immune dysfunction, tissue damage, and inflammation pathways. Toxicol Pathol 43:171-185. http://dx.doi.org/10.1177/0192623314537885. [5]

Blair A, Hines CJ, Thomas KW, Alavanja MCR, Freeman LEB, Hoppin JA, Kamel F, Lynch CF, Lubin JH, Silverman DT, Whelan E, Zahm SH, Sandler DP. 2015. Investing in prospective cohorts for etiologic study of occupational exposures. Am J Ind Med 58:113-122. http://dx.doi.org/10.1002/ajim.22403. [5]

Bonzo JA, Rose K, Freeman K, Deibert E, Amaral KB, Ferguson SS, Andersen ME, Witek RP, LeCluyse EL. 2015. Differential effects of trovafloxacin on TNF-α and IL-6 profiles in a rat hepatocyte–kupffer cell coculture system. Applied In Vitro Toxicology 1:45-54. http://dx.doi.org/10.1089/aivt.2014.0004. [5]

Bourdon-Lacombe JA, Moffat ID, Deveau M, Husain M, Auerbach S, Krewski D, Thomas RS, Bushel PR, Williams A, Yauk CL. 2015. Technical guide for applications of gene expression profiling in human health risk assessment of environmental chemicals. Regul Toxicol Pharmacol 72:292-309. http://dx.doi.org/10.1016/j.yrtph.2015.04.010. [5]

Browne P, Judson RS, Casey WM, Kleinstreuer NC, Thomas RS. 2015. Screening chemicals for estrogen receptor bioactivity using a computational model. Environ Sci Technol 49:8804-8814. http://dx.doi.org/10.1021/acs.est.5b02641. [5]

Buskirk AD, Green BJ, Lemons AR, Nayak AP, Goldsmith WT, Kashon ML, Anderson SE, Hettick JM, Templeton SP, Germolec DR, Beezhold DH. 2014. A murine inhalation model to characterize pulmonary exposure to dry Aspergillus fumigatus conidia. PLoS One 9. http://dx.doi.org/10.1371/journal.pone.0109855. [1, 5]

Camacho L, Basavarajappa MS, Chang CW, Han T, Kobets T, Koturbash I, Surratt G, Lewis SM, Vanlandingham MM, Fuscoe JC, Gamboa da Costa G, Pogribny IP, Delclos KB. 2015. Effects of oral exposure to bisphenol A on gene expression and global genomic DNA methylation in the prostate, female mammary gland, and uterus of NCTR Sprague-Dawley rats. Food Chem Toxicol 81:92-103. http://dx.doi.org/10.1016/j.fct.2015.04.009. [3]

Casey W, Jacobs A, Maull E, Matheson J, Clarke C, Lowit A. 2015. A new path forward: The Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM) and National Toxicology Program's Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM). J Am Assoc Lab Anim Sci 54:170-173. http://www.ingentaconnect.com/content/aalas/jaalas/2015/00000054/00000002/art00008?token=0053149d9b466720297d76345f7b552b2f5f73516f354b6d3f6a4b6061585e4e6b6331761996d4d4cfb. [5]

Ceger P, Allen D, Huang R, Xia M, Casey W. 2015. Performance of the BG1Luc ER TA method in a qHTS format. ALTEX 32:287-296. http://dx.doi.org/10.14573/altex.1505121. [5]

Cena LG, Keane MJ, Chisholm WP, Stone S, Harper M, Chen BT. 2014. A novel method for assessing respiratory deposition of welding fume nanoparticles. J Occup Env Hyg 11:771-780. http://dx.doi.org/10.1080/15459624.2014.919393. [2]

Chang X, Kleinstreuer N, Ceger P, Hsieh J-H, Allen D, Casey W. 2014. Application of reverse dosimetry to compare in vitro and in vivo estrogen receptor activity. Applied In Vitro Toxicology 1:33-44. http://dx.doi.org/10.1089/aivt.2014.0005. [5]

Chango A, Pogribny IP. 2015. Considering maternal dietary modulators for epigenetic regulation and programming of the fetal epigenome. Nutrients 7:2748-2770. http://dx.doi.org/10.3390/nu7042748. [4]

Chen S, Hsieh JH, Huang R, Sakamuru S, Hsin LY, Xia M, Shockley KR, Auerbach S, Kanaya N, Lu H, Svoboda D, Witt KL, Merrick BA, Teng CT, Tice RR. 2015. Cell-based high-throughput screening for aromatase inhibitors in the Tox21 10K library. Toxicol Sci 147:446-457. http://dx.doi.org/10.1093/toxsci/kfv141. [5]

Chen S, Zhang Z, Wu Y, Shi Q, Yan H, Mei N, Tolleson WH, Guo L. 2015. Endoplasmic reticulum stress and store-operated calcium entry contribute to usnic acid-induced toxicity in hepatic cells. Toxicol Sci 146:116-126. http://dx.doi.org/10.1093/toxsci/kfv075. [4]

Chen X, Hansen DK, Merry G, DeJarnette C, Nolen G, Sloper D, Fisher JE, Harrouk W, Tassinari MS, Inselman AL. 2015. Developing osteoblasts as an endpoint for the mouse embryonic stem cell test. Reprod Toxicol 53:131-140. http://dx.doi.org/10.1016/j.reprotox.2015.04.008. [4]

Cheng J, Dackor RT, Bradbury JA, Li H, DeGraff LM, Hong LK, King D, Lih FB, Gruzdev A, Edin ML, Travlos GS, Flake GP, Tomer KB, Zeldin DC. 2015. Contribution of alveolar type II cell-derived cyclooxygenase-2 to basal airway function, lung inflammation, and lung fibrosis. FASEB J. http://dx.doi.org/10.1096/fj.14-268458. [5]

Chirila MM, Sarkisian K, Andrew ME, Kwon C-W, Rando RJ, Harper M. 2015. A comparison of two laboratories for the measurement of wood dust using button sampler and diffuse reflection infrared fourier-transform spectroscopy (DRIFTS). Ann Occup Hyg 59:336-346. http://dx.doi.org/10.1093/annhyg/meu096. [2]

Chrysovergis K, Wang X, Kosak J, Lee SH, Kim JS, Foley JF, Travlos G, Singh S, Baek SJ, Eling TE. 2014. NAG-1/GDF-15 prevents obesity by increasing thermogenesis, lipolysis and oxidative metabolism. Int J Obes (Lond) 38:1555-1564. http://dx.doi.org/10.1038/ijo.2014.27. [5]

Churchwell MI, Scheri RC, Von Tungeln LS, Gamboa da Costa G, Beland FA, Doerge DR. 2015. Evaluation of serum and liver toxicokinetics for furan and liver DNA adduct formation in male Fischer 344 rats. Food Chem Toxicol 86:1-8. http://dx.doi.org/10.1016/j.fct.2015.08.029. [3]

Consortium SM-I. 2014. A comprehensive assessment of RNA-seq accuracy, reproducibility and information content by the Sequencing Quality Control Consortium. Nat Biotechnol 32:903-914. http://dx.doi.org/10.1038/nbt.2957. [5]

Cora MC, Kooistra L, Travlos G. 2015. Vaginal cytology of the laboratory rat and mouse: Review and criteria for the staging of the estrous cycle using stained vaginal smears. Toxicol Pathol. http://dx.doi.org/10.1177/0192623315570339. [5]

Costa C, Garcia-Leston J, Costa S, Coelho P, Silva S, Pingarilho M, Valdiglesias V, Mattei F, Dall'Armi V, Bonassi S, Laffon B, Snawder J, Teixeira JP. 2014. Is organic farming safer to farmers' health? A comparison between organic and traditional farming. Toxicol Lett 230:166-176. http://dx.doi.org/10.1016/j.toxlet.2014.02.011. [2]

Curwin BD, Deddens JA, McKernan LT. 2015. Flavoring exposure in food manufacturing. J Expo Sci Environ Epidemiol 25:324-333. http://dx.doi.org/10.1038/jes.2014.52. [1]

Cyphert JM, Carlin DJ, Nyska A, Schladweiler MC, Ledbetter AD, Shannahan JH, Kodavanti UP, Gavett SH. 2015. Comparative long-term toxicity of libby amphibole and amosite asbestos in rats after single or multiple intratracheal exposures. J Toxicol Environ Health, A: Curr Iss 78:151-165. http://dx.doi.org/10.1080/15287394.2014.947455. [5]

Dahm MM, Bertke S, Allee S, Daniels RD. 2015. Creation of a retrospective job-exposure matrix using surrogate measures of exposure for a cohort of US career firefighters from San Francisco, Chicago and Philadelphia. Occup Environ Med 72:670-677. http://dx.doi.org/10.1136/oemed-2014-102790. [2]

Dahm MM, Schubauer-Berigan MK, Evans DE, Birch ME, Fernback JE, Deddens JA. 2015. Carbon nanotube and nanofiber exposure assessments: An analysis of 14 site visits. Ann Occup Hyg 59:705-723. http://dx.doi.org/10.1093/annhyg/mev020. [2]

Davenport LL, Hsieh H, Eppert BL, Carreira VS, Krishan M, Ingle T, Howard PC, Williams MT, Vorhees CV, Genter MB. 2015. Systemic and behavioral effects of intranasal administration of silver nanoparticles. Neurotoxicol Teratol 51:68-76. http://dx.doi.org/10.1016/j.ntt.2015.08.006. [4]

Davis FM, Janoshazi A, Janardhan KS, Steinckwich N, D'Agostin DM, Petranka JG, Desai PN, Roberts-Thomson SJ, Bird GS, Tucker DK, Fenton SE, Feske S, Monteith GR, Putney JW, Jr. 2015. Essential role of Orai1 store-operated calcium channels in lactation. Proc Natl Acad Sci U S A 112:5827-5832. http://dx.doi.org/10.1073/pnas.1502264112. [5]

de Conti A, Kobets T, Tryndyak V, Burnett SD, Han T, Fuscoe JC, Beland FA, Doerge DR, Pogribny IP. 2015. Persistence of furan-induced epigenetic aberrations in the livers of F344 rats. Toxicol Sci 144:217-226. http://dx.doi.org/10.1093/toxsci/kfu313. [3]

Desai VG, Kwekel JC, Vijay V, Moland CL, Herman EH, Lee T, Han T, Lewis SM, Davis KJ, Muskhelishvili L, Kerr S, Fuscoe JC. 2014. Early biomarkers of doxorubicin-induced heart injury in a mouse model. Toxicol Appl Pharmacol 281:221-229. http://dx.doi.org/10.1016/j.taap.2014.10.006. [4]

Didion JP, Morgan AP, Clayshulte AMF, McMullan RC, Yadgary L, Petkov PM, Bell TA, Gatti DM, Crowley JJ, Hua K, Aylor DL, Bai L, Calaway M, Chesler EJ, French JE, Geiger TR, Gooch TJ, Garland T, Jr., Harrill AH, Hunter K, McMillan L, Holt M, Miller DR, O'Brien DA, Paigen K, Pan W, Rowe LB, Shaw GD, Simecek P, Sullivan PF, Svenson KL, Weinstock GM, Threadgill DW, Pomp D, Churchill GA, Pardo-Manuel de Villena F. 2015. A multi-megabase copy number gain causes maternal transmission ratio distortion on mouse chromosome 2. PLoS Genet 11:e1004850. http://dx.doi.org/10.1371/journal.pgen.1004850. [5]

Dixon D, Alison R, Bach U, Colman K, Foley GL, Harleman JH, Haworth R, Herbert R, Heuser A, Long G, Mirsky M, Regan K, Van Esch E, Westwood FR, Vidal J, Yoshida M. 2014. Nonproliferative and proliferative lesions of the rat and mouse female reproductive system. J Toxicol Pathol 27:1s-107s. http://dx.doi.org/10.1293/tox.27.1S. [5]

Dunnick JK, Sanders JM, Kissling GE, Johnson C, Boyle MH, Elmore SA. 2014. Environmental chemical exposure may contribute to uterine cancer development: Studies with tetrabromobisphenol A. Toxicol Pathol. http://dx.doi.org/10.1177/0192623314557335. [5]

Dunnick KM, Pillai R, Pisane KL, Stefaniak AB, Sabolsky EM, Leonard SS. 2015. The effect of cerium oxide nanoparticle valence state on reactive oxygen species and toxicity. Biol Trace Elem Res. http://dx.doi.org/10.1007/s12011-015-0297-4. [2]

Duquenne P, Simon X, Demange V, Harper M, Wild P. 2015. Endotoxin deposits on the inner surfaces of closed-face cassettes during bioaerosol sampling: a field investigation at composting facilities. Ann Occup Hyg 59:504-513. http://dx.doi.org/10.1093/annhyg/meu108. [2]

Dymacek J, Snyder-Talkington BN, Porter DW, Mercer RR, Wolfarth MG, Castranova V, Qian Y, Guo NL. 2015. mRNA and miRNA regulatory networks reflective of multi-walled carbon nanotube-induced lung inflammatory and fibrotic pathologies in mice. Toxicol Sci 144:51-64. http://dx.doi.org/10.1093/toxsci/kfu262. [2]

Eduati F, Mangravite LM, Wang T, Tang H, Bare JC, Huang RL, Norman T, Kellen M, Menden MP, Yang JC, Zhan XW, Zhong R, Xiao GH, Xia MH, Abdo N, Kosyk O, Friend S, Dearry A, Simeonov A, Tice RR, Rusyn I, Wright FA, Stolovitzky G, Xie Y, Saez-Rodriguez J, Niehs-Ncats-Unc D. 2015. Prediction of human population responses to toxic compounds by a collaborative competition. Nat Biotechnol 33:933-U172. http://dx.doi.org/10.1038/nbt.3299. [5]

Edwards JK, McGrath LJ, Buckley JP, Schubauer-Berigan MK, Cole SR, Richardson DB. 2014. Occupational radon exposure and lung cancer mortality: estimating intervention effects using the parametric g-formula. Epidemiology 25:829-834. http://dx.doi.org/10.1097/ede.0000000000000164. [2]

Elmore SA, Cora MC, Gruebbel MM, Hayes SA, Hoane JS, Koizumi H, Peters R, Rosol TJ, Singh BP, Szabo KA. 2014. Proceedings of the 2014 National Toxicology Program Satellite Symposium. Toxicol Pathol. http://dx.doi.org/10.1177/0192623314555526. [5]

Esswein EJ, Snawder J, King B, Breitenstein M, Alexander-Scott M, Kiefer M. 2014. Evaluation of some potential chemical exposure risks during flowback operations in unconventional oil and gas extraction: Preliminary results. J Occup Env Hyg 11:D174-D184. http://dx.doi.org/10.1080/15459624.2014.933960. [2]

Faber MA, Sabato V, Bridts CH, Nayak A, Beezhold DH, Ebo DG. 2015. Clinical relevance of the Hevea brasiliensis lipid transfer protein Hev b 12. J Allergy Clin Immunol 135:1645-1648.e1641. http://dx.doi.org/10.1016/j.jaci.2014.12.1919. [2]

Fang JL, Vanlandingham M, da Costa GG, Beland FA. 2014. Absorption and metabolism of triclosan after application to the skin of B6C3F1 mice. Environ Toxicol. http://dx.doi.org/10.1002/tox.22074. [3]

Fang JL, Vanlandingham M, Juliar BE, Olson G, Patton RE, Beland FA. 2015. Dose-response assessment of the dermal toxicity of triclosan in B6C3F1 mice. Toxicology Research 4:867-877. http://dx.doi.org/10.1039/c4tx00152d. [3]

Fennell TR, Morgan DL, Watson SL, Dhungana S, Waidyanatha S. 2015. Systemic uptake, albumin and hemoglobin binding of [(14)C]2,3-butanedione administered by intratracheal instillation in male Harlan Sprague Dawley rats and oropharyngeal aspiration in male B6C3F1/N mice. Chem Biol Interact 227:112-119. http://dx.doi.org/10.1016/j.cbi.2014.12.029. [5]

Fenton SE, Birnbaum LS. 2015. Timing of environmental exposures as a critical element in breast cancer risk. J Clin Endocrinol Metab 100:3245-3250. http://dx.doi.org/10.1210/jc.2015-2848. [5]

Ferguson SA, Delbert Law C, Sahin L, Montenegro SV. 2014. Effects of perinatal methylphenidate (MPH) treatment on postweaning behaviors of male and female Sprague-Dawley rats. Neurotoxicol Teratol 47c:125-136. http://dx.doi.org/10.1016/j.ntt.2014.12.002. [4]

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[1] Funded by the NIEHS/NIOSH Interagency Agreement

[2] Funded by NIOSH voluntary allocations to the NTP

[3] Funded by the NIEHS/NCTR Interagency Agreement

[4] Funded by NCTR voluntary allocations to the NTP

[5] Funded by NIEHS voluntary allocations to the NTP

[6] Funded by the NIEHS/EPA Interagency Agreement


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