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Annual Report for Fiscal Year 2015

Annual Report for Fiscal Year 2015
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https://ntp.niehs.nih.gov/go/789913

NTP Scientists Presented SAN Trimer Results at Toms River Public Meeting

On February 4, 2015, the U.S. Environmental Protection Agency (EPA) held a public meeting to update the community about the Reich Farm Superfund site in Toms River, Ocean County, New Jersey. EPA invited NTP scientists to discuss their studies on styrene-acrylonitrile trimer, also known as SAN trimer. SAN trimer was one of the contaminants at the site and is a byproduct of manufacturing acrylonitrile styrene plastic.

Due to a lack of scientific information about SAN trimer, EPA asked NTP to study the chemical. After an extensive design, study, and peer-review process, NTP published its results in 2012 in NTP Technical Report 573. NTP found no evidence that SAN trimer caused cancer in male and female rats. Some noncancer effects, such as peripheral nerve damage in the exposed male and female rats, were reported. EPA is using NTP findings, along with other data, to establish cleanup levels for the Superfund site.
Dr. Behl and Dr. Elmore

Mamta Behl, Ph.D., a neurotoxicologist with NTP, was at the meeting to discuss the research on SAN trimer. Susan Elmore, D.V.M., a scientist in the NTP Pathology Group, presented the SAN trimer pathology findings. (Photo courtesy of Steve McCaw)