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Annual Report for Fiscal Year 2015

Annual Report for Fiscal Year 2015
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https://ntp.niehs.nih.gov/go/792699

Disposition, Metabolism, and Toxicokinetic Studies

Complete dosimetry of a chemical or physical agent describes its absorption, distribution, metabolism, and excretion in the body in both humans and test animals at differing levels of exposure, over all ages, via several routes of exposure, and under varying genetic backgrounds. Substances evaluated during FY 2015 are listed in the table below.

Chemical CASRN* Species Route Study Scientist Status
Bisphenol A 80-05-7 Rats In-vitro Declos Completed
Bisphenol S 80-09-1 Mice, Rats Gavage, Intravenous Sutherland Ongoing
1,3-Dichloro-2-propanol 96-23-1 Mice, Rats Gavage Chan Completed
Ethylene glycol 2-ethylhexyl ether 1559-35-9 Mice, Rats Gavage Blystone Completed

*CASRN = Chemical Abstracts Service Registry Number