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Annual Report for Fiscal Year 2015

Annual Report for Fiscal Year 2015
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https://ntp.niehs.nih.gov/go/792712

Genetic Toxicity

Genetic toxicity test results are used to help interpret general toxicity, carcinogenicity, or other in vivo test results, and provide a database for use in structure-activity relationship analysis. Substances tested for genetic toxicity during FY 2015 are listed in the table below.

Genetic Toxicity Studies During FY 2015
Test Article CASRN* Species Testing Battery Status
Aspergillus fumigatus mold N/A Salmonella Salmonella Completed
Aspergillus fumigatus mold N/A Mice Micronucleus Initiated
3'-Azido-3'-deoxythymidine  30516-87-1 Salmonella Salmonella Completed
Bisphenol AF 1478-61-1 Rats Micronucleus Completed
Black cohosh 84776-26-1 Salmonella Salmonella Ongoing
n-Butyl glycidyl ether 2426-08-6 Mice Micronucleus Ongoing
n-Butyl glycidyl ether 2426-08-6 Rats Micronucleus Ongoing
1-Butyl-3-methylimidazolium chloride 79917-90-1 Rats Micronucleus Completed
1-Butyl-3-methylimidazolium chloride 79917-90-1 Mice Micronucleus Completed
1-Butyl-1-methylpyrrolidinium chloride 479500-35-1 Rats Micronucleus Completed
1-Butyl-1-methylpyrrolidinium chloride 479500-35-1 Mice Micronucleus Completed
N-Butylpyridinium chloride 1124-64-7 Mice Micronucleus Completed
N-Butylpyridinium chloride 1124-64-7 Rats Micronucleus Ongoing
Corn oil 8001-30-7 Rats Micronucleus Ongoing
Dimethyl 1,4-cyclohexanedicarboxylate 94-60-0 Salmonella Salmonella Completed
1,4-Cyclohexanedimethanol 105-08-8 Salmonella Salmonella Completed
Dimethylamine borane 74-94-2 Salmonella Salmonella Completed
2,2'-Dimorpholinodiethyl ether 6425-39-4 Salmonella Salmonella Initiated
Dipropylene glycol phenyl ether 51730-94-0 Salmonella Salmonella Completed
Dowanol DiPPh glycol ether N/A Salmonella Salmonella Completed
Echinacea purpurea extract 90028-20-9 Salmonella Salmonella Initiated
1-Ethyl-3-methylimidazolium chloride 65039-09-0 Rats Micronucleus Completed
1-Ethyl-3-methylimidazolium chloride 65039-09-0 Mice Micronucleus Completed
4-Methoxymethylcyclohexylmethanol 98955-27-2 Salmonella Salmonella Completed
4-Methylcyclohexanemethanol, crude N/A Rats Micronucleus Completed
4-Methylcyclohexanemethanol, crude N/A Salmonella Salmonella Completed
Methyl 4-methylcyclohexanecarboxylate 51181-40-9 Salmonella Salmonella Completed
2-Methylcyclohexanemethanol 2105-40-0 Salmonella Salmonella Completed
4-Methylcyclohexanemethanol 34885-03-5 Rats Micronucleus Completed
4-Methylcyclohexanemethanol 34885-03-5 Salmonella Salmonella Completed
2-Nitro-2-ethyl-1,3-propanediol 597-09-1 Salmonella Salmonella Ongoing
Perfluorodecanoic acid 335-76-2 Rats Micronucleus Ongoing
2-Nitro-1-propanol 2902-96-7 Salmonella Salmonella Completed
Propylene glycol phenyl ether 770-35-4 Rats Micronucleus Completed
Propylene glycol phenyl ether 770-35-4 Salmonella Salmonella Completed
Sulfolane 126-33-0 Mice Micronucleus Completed
Sulfolane 126-33-0 Rats Micronucleus Completed
Tris(Chloropropyl)phosphate 13674-84-5 Salmonella Salmonella Completed
Vinpocetine 42971-09-5 Salmonella Salmonella Completed
Vinpocetine 42971-09-5 Mice Micronucleus Initiated
Zinc carbonate, basic 5263-02-5 Rats Micronucleus Ongoing

*CASRN = Chemical Abstracts Service Registry Number