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Annual Report for Fiscal Year 2015

Annual Report for Fiscal Year 2015

ICCVAM Activities

NICEATM provided support for seven teleconferences and two in-person meetings held by ICCVAM in FY 2015. NICEATM also supported two ad hoc ICCVAM working groups, one focused on skin sensitization and the other on reference chemicals for validation of in vitro androgen receptor assays.

The first ICCVAM Communities of Practice webinar was held on January 27, 2015. The webinar focused on the development and application of reverse toxicokinetic models for extrapolation of high throughput screening data to in vivo dosimetry. John Wambaugh, Ph.D. from the EPA National Center for Computational Toxicology (NCCT), provided an overview of the development of reverse toxicokinetic models. Barbara Wetmore, Ph.D., from the Hamner Institutes for Health Sciences discussed the consideration of population variability and sensitive subpopulations in the use of these models. NICEATM and NCCT hosted the webinar on behalf of ICCVAM. Slide presentations and a video recording of the webinar are available on the NTP website.  

ICCVAM, with NICEATM support, held its second public forum May 27, 2015, at NIH in Bethesda, Maryland. This meeting provided an opportunity for public interaction with representatives from the 15 member agencies of ICCVAM. ICCVAM members provided information about their agency’s activities relevant to the development and use of alternative test methods. Individuals and groups interested in promoting alternative methods or reducing animal use in testing presented public comments. The agenda and presentations are available on the NTP website.

ICCVAM agency activities that support replacement, reduction, and refinement of animal use can be found on the NTP website. NICEATM is also working with the NIEHS Office of Communications and Public Liaison to explore how social media, such as Twitter and LinkedIn, might be used to improve communication with stakeholders and facilitate collaboration.

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