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Annual Report for Fiscal Year 2015

Annual Report for Fiscal Year 2015
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https://ntp.niehs.nih.gov/go/792802

Project Review Committee Approved

The table below lists studies that were approved by either the internal NIEHS/NTP protocol approval committee or the internal NIEHS/NTP project review committee, but were not started during FY 2015.

Protocol Title Study Scientist
Evaluation of the immunotoxicity of sulfolane (CASRN* 126-33-0) in B6C3F1/N mice treated for 90-days via oral gavage Germolec
Evaluation of the immunotoxicity of sulfolane (CASRN 126-33-0) in harlan sprague dawley rats following perinatal exposure via dosed drinking water Germolec
Toxicokinetic studies of sulfolane (CASRN 126-33-0) in harlan sprague dawley rats and B6C3F1/N mice following administration via gavage, intravenous, and drinking water Waidyanatha/ Blystone
Chronic toxicity and carcinogenicity studies of 1020 long multiwalled carbon nanotubes in harlan sprague dawley rats and B6C3F1/N mice exposed via whole body inhalation Germolec
Evaluation of the immunotoxicity of 1020 long multiwalled carbon nanotubes in harlan sprague dawley rats exposed via whole body inhalation for 30-days and B6C3F1/N mice exposed via whole body inhalation for 30-days or 3-months Germolec
Acute toxicity studies of trimethylsilyldiazomethane (TMSD) (CASRN 18107-18-1) in male harlan sprague dawley rats and B6C3F1/N mice exposed via nose only inhalation Gwinn
Evaluation of the prechronic toxicity of Valerian (V. officinalis) in B6C3F1/N mice treated via gavage Roberts
Evaluation of a perinatal dose range finding study of Valerian (V. officinalis) in harlan sprague dawley rats administered daily via gavage Roberts
Toxicokinetic studies of vinpocetine (CASRN 42971-09-5) in pregnant harlan sprague dawley rats following gavage administration Catlin
Perinatal dose range-finding study of 2,2’ –dimorpholinodiethyl ether (DMDEE) (CASRN 6425-39-4) in harlan sprague dawley rats exposed via gavage Roberts
4-week toxicity study of 2,2’ –dimorpholinodiethyl ether (DMDEE) (CASRN 6425-39-4) in B6C3F1/N mice treated via gavage Roberts
Combined prenatal and perinatal dose range-finding study of efavirenz (CASRN 154598-52-4) in CD-1 mice exposed via gavage McIntyre
Combined prenatal and perinatal dose range-finding study of tenofovir disoproxil fumarate (CASRN 202138-50-9) in CD-1 mice exposed via gavage McIntyre
Perinatal dose range-finding study of bisphenol S (CASRN 80-09-1) in harlan sprague dawley rats exposed via dosed feed Sutherland
Two-week toxicity of bisphenol S (CASRN 80-09-1) in B6C3F1/N mice exposed via dosed feed Sutherland
Subchronic toxicity of Aspergillus versicolor in B6C3F1/N mice exposed via nose only inhalation Germolec
Prenatal toxicity study of vinpocetine (CASRN 42971-09-5) in new zealand white rabbits administered via gavage Catlin
Perinatal dose range-finding study of triclocarban (CASRN 101-20-2) in harlan sprague dawley rats exposed via oral gavage Sutherland
Two-week toxicity of triclocarban (CASRN 101-20-2) in B6C3F1/N mice exposed via oral gavage Sutherland
Perinatal dose range-finding study of triclosan (CASRN 3380-34-5) in harlan sprague dawley rats exposed via oral gavage Sutherland
Absorption, distribution, metabolism, and excretion (ADME) studies of bisphenol S (CASRN 80-09-1) in harlan sprague dawley rats and B6C3F1/N mice following gavage administration and intravenous administration of [14C]bisphenol S and for investigating clearance and metabolism of selected bisphenol S derivatives in vitro Sutherland
Subchronic toxicity of Stachybotrys chartarum (CASRN 67892-26-6) in B6C3F1/N mice exposed via nose only inhalation Germolec
Perinatal dose range-finding study of Echinacea purpurea extract (CASRN 90028-20-9) in harlan sprague dawley rats exposed via oral gavage Ryan
Prechronic toxicity of N-butylbenzenesulfonamide (CASRN 3622-84-2) in B6C3F1/N mice exposed via dosed feed Rider
Five-day toxicity and toxicogenomics study of five lots of Ginkgo biloba extract (CASRN 90045-36-6), goldenseal extract (CASRN 84603-60-1) and green tea extract, and toxicokinetic study in one lot of Ginkgo biloba extract in F344/NTac rats treated via oral gavage Rider
Five-day toxicity and toxicogenomics study of brominated flame retardants in male harlan spraque dawley rats treated via oral gavage Dunnick
Perinatal study to investigate the endocrine toxicity of tris(4-chlorophenyl)methane (CASRN 27575-78-6) in harlan sprague dawley rats exposed via dosed feed Catlin
*CASRN = Chemical Abstracts Service Registry Number