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Annual Report for Fiscal Year 2015

Annual Report for Fiscal Year 2015

Testing and Toxicology Studies

The NTP testing program evaluates substances for a variety of health-related effects, generally using rodent models for study. For each test article studied, a study scientist designs a comprehensive testing strategy to address the identified research and testing needs to fully characterize its toxic potential, and a project review committee evaluates the strategy. Reports and summaries of NTP toxicity studies including carcinogenicity, and effects on development and reproduction, are available on the NTP website.

The following Division of NTP branches at NIEHS are involved in the testing program: Biomolecular Screening Branch, led by Raymond Tice, Ph.D. until his retirement in December 2014, and now led by acting chief Rick Paules, Ph.D.; Cellular and Molecular Pathology Branch, led by Robert Sills, D.V.M., Ph.D.; NTP Laboratory, led by acting chief Michael Devito, Ph.D.; Program Operations Branch, led by Michelle Hooth, Ph.D.; and Toxicology Branch, led by Paul Foster, Ph.D.

New studies that implement plans outlined in research concepts from prior years are listed in this section. Of note are the multiple study types initiated, scheduled, or approved: aromatic phosphates including isopropylated phenol phosphate and triphenyl phosphate; bisphenol S; C9 alkylbenzenes including cumene, 2-ethyltoluene, 3-ethyltoluene, and 4-ethyltoluene; ethylene glycol 2-ethylhexyl ether; polycyclic aromatic compounds including benzo(a)pyrene and phenanthrene; sulfolane; and valerian root extract.