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Annual Report for Fiscal Year 2016

Annual Report for Fiscal Year 2016

RoC Substances Selected for Evaluation

Study Scientist
Primary Uses/Exposures Listing Status and Rationale
Goldenseal Root Powder (Hydrastis canadensis)
Office of RoC staff
Herbal remedy (botanical product) used to treat gastrointestinal disturbances, urinary disorders, hemorrhage, skin, mouth, and eye infections and inflammation. NTP Board of Scientific Counselors review of draft concept, April 2014.
Haloacetic Acids Found as Water Disinfection By-Products
Gloria Jahnke 
13 individual haloacetic acids or potential class or subclass of these haloacetic acids. People are exposed to these haloacetic acids by ingestion of chlorinated drinking water and by dermal contact or breathing compounds during bathing or using swimming pools and spas that use chlorine for disinfection. NTP Board of Scientific Counselors review of draft concept, April 2016.
Helicobacter pylori (H. pylori): Chronic Infection
Ruth Lunn 
Gram negative, multi-flagellated bacterium that colonizes the stomach and causes peptic ulcer. Bacterium is spread by person-to-person contact especially among family member. Routes of exposure include oral-oral, fecal-oral, iatrogenic, and possibly from contaminated water. Risks factors for infection include age, race, socioeconomic status such as crowded living conditions, and poor sanitation/hygiene. NTP Board of Scientific Counselors review of draft concept, April 2016.
Shift Work at Night, Light at Night, and Circadian Disruption
Ruth Lunn
Unnatural (e.g., such as ill-timed) electrical light, especially light-at-night (LAN), may disrupt sleep and biological processes controlled by endogenous circadian clocks. People, who by virtue of the nature of their work, lifestyle choices, or residence, are subjected to exposure to unnatural LAN. Shift workers who work at night or evenings starting before 6:00 a.m. can experience an extreme type of LAN exposure, as well as changes in other activities related to LAN, such as changes in daily activities, eating sleeping, lifestyle factors, and social behavior.  Workshop: Shift Work at Night, Artificial Light at Night, and Circadian Disruption workshop, March 2016

Additional Links for the RoC