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Annual Report for Fiscal Year 2016

Annual Report for Fiscal Year 2016


NTP Reports and Documents

Ashley K, O’Connor PF. Purpose, scope and use of the NIOSH manual of analytical methods. In: NIOSH manual of analytical methods, fifth edition. Ashley K, O'Connor PF, editors. Cincinnati (OH): U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, DHHS (NIOSH) Publication No. 2014-151, 2016 Apr;PS1-PS9; https://www.cdc.gov/niosh/docs/2014-151/pdfs/chapters/chapter-ps.pdf.

Birch EM. Monitoring diesel exhaust in the workplace. In: NIOSH manual of analytical methods, fifth edition. Ashley K, O'Connor PF, editors. Cincinnati (OH): U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, DHHS (NIOSH) Publication No. 2014-151, 2016 Apr;DL1-DL41. https://www.cdc.gov/niosh/docs/2014-151/pdfs/chapters/chapter-dl.pdf.

Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM) 2014-2015 Biennial Progress Report. National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods. Research Triangle Park (NC): National Toxicology Program. 2016. https://ntp.niehs.nih.gov/go/2015iccvamreport.

NTP Research Report on the Systematic Review of the Effects of Fluoride on Learning and Memory in Animal Studies. Research Triangle Park (NC): National Toxicology Program. Natl Toxicol Program Res Rep Ser. 2016 Jul;(RR-01):1-132; https://ntp.niehs.nih.gov/ntp/results/pubs/rr/reports/rr01_508.pdf.

NTP Research Report on Organotin and Total Tin Levels in Danish Women on Reproductive Age. Research Triangle Park (NC): National Toxicology Program. Natl Toxicol Program Rep Ser. 2016 Jul;(RR-02):1-27; https://ntp.niehs.nih.gov/ntp/results/pubs/rr/reports/rr02_508.pdf.

NTP Technical Report on the Toxicity Studies of p-Toluenesulfonamide (CAS No. 70-55-3) Administered in Feed to F344/N Rats, F344/NTac Rats, and B6C3F1/N Mice. Research Triangle Park (NC): National Toxicology Program. Natl Toxicol Program Tox Rep Ser.2016 Aug;(88):1-48; https://ntp.niehs.nih.gov/ntp/htdocs/st_rpts/tox88_508.pdf.

NTP Technical Report on the Toxicity Studies of Octahydro-tetramethyl-naphthalenyl-ethanone (OTNE) Administered Dermally to F344/NTac Rats and B6C3F1/N Mice. Research Triangle Park (NC): National Toxicology Program. Natl Toxicol Program Tox Rep Ser. 2016 Jun;(92):1-58; https://ntp.niehs.nih.gov/ntp/htdocs/st_rpts/tox092_508.pdf

NTP Technical Report on the Toxicity Studies of α-Pinene (CAS No. 80-56-8) Administered by Inhalation to F344/N Rats and B6C3F1/N Mice. Research Triangle Park (NC): National Toxicology Program. Natl Toxicol Program Tox Rep Ser. 2016 May;(81):1-58; https://ntp.niehs.nih.gov/ntp/htdocs/st_rpts/tox081_508.pdf.

NTP Technical Report on the Toxicity Studies of Sodium Thioglycolate (CAS No. 367-51-1) Administered Dermally to F344/N Rats and B6C3F1/N Mice. Research Triangle Park (NC): National Toxicology Program. Natl Toxicol Program Tox Rep Ser. 2016 May;(80):1-46; https://ntp.niehs.nih.gov/ntp/htdocs/st_rpts/tox080_508.pdf.

NTP Technical Report on the Toxicology Studies of a Pentabromodiphenyl Ether Mixture [DE-71 (Technical Grade)] (CAS No. 32534-81-9) in F344/N Rats and B6C3F1/N Mice and Toxicology and Carcinogenesis Studies of a Pentabromodiphenyl Ether Mixture [DE-71 (Technical Grade)] in Wistar Han [Crl:WI(Han)] Rats and B6C3F1/N Mice (Gavage Studies). Research Triangle Park (NC): National Toxicology Program. Natl Toxicol Program Tech Rep Ser. 2016 Feb;(589):1-304; https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr589_508.pdf.

NTP Technical Report on the Toxicity Studies of 5-Amino-o-cresol Administered Dermally to F344/NTac Rats and B6C3F1/N Mice (CAS No. 2835-95-2). Research Triangle Park (NC): National Toxicology Program. Natl Toxicol Program Tox Rep Ser. 2015 Nov;(89):1-40; https://ntp.niehs.nih.gov/ntp/htdocs/st_rpts/tox089_508.pdf.

Report on Carcinogens, Fourteenth Edition. Research Triangle Park (NC): National Toxicology Program. U.S. Department of Health and Human Services, Public Health Service. 2016; http://ntp.niehs.nih.gov/go/roc14

Report on Carcinogens Monograph on Epstein-Barr Virus. Research Triangle Park (NC): National Toxicology Program. Rep Carcinog Monogr. 2016 Aug;1-72; https://ntp.niehs.nih.gov/ntp/roc/monographs/ebv_final201608_508.pdf.

Report on Carcinogens Monograph on Human Immunodeficiency Virus Type 1. Research Triangle Park (NC): National Toxicology Program. Rep Carcinog Monogr. 2016 Aug;1-108; https://ntp.niehs.nih.gov/ntp/roc/monographs/hiv_final201608_508.pdf.

Report on Carcinogens Monograph on Human T-cell Lymphotropic Virus Type 1. Research Triangle Park (NC): National Toxicology Program. Rep Carcinog Monogr. 2016 Aug;1-44; https://ntp.niehs.nih.gov/ntp/roc/monographs/htlv_final201608_508.pdf.

Report on Carcinogens Monograph on Kaposi Sarcoma-Associated Herpesvirus. Research Triangle Park (NC): National Toxicology Program. Rep Carcinog Monogr. 2016 Aug;1-69; https://ntp.niehs.nih.gov/ntp/roc/monographs/kshv_final201608_508.pdf.

Report on Carcinogens Monograph on Merkel Cell Polyomavirus. Research Triangle Park (NC): National Toxicology Program. Rep Carcinog Monogr. 2016 Aug;1-52; https://ntp.niehs.nih.gov/ntp/roc/monographs/mcv_final201608_508.pdf.

Report on Carcinogens Monograph on Cobalt and Cobalt Compounds that Release Cobalt Ions In Vivo. Research Triangle Park (NC): National Toxicology Program. Rep Carcinog Monogr. 2016 Apr;1-214; https://ntp.niehs.nih.gov/ntp/roc/monographs/cobalt_final_508.pdf.

Report on Carcinogens Monograph on Trichloroethylene. Research Triangle Park (NC): National Toxicology Program. Rep Carcinog Monogr. 2015 Jan;1-254; https://ntp.niehs.nih.gov/ntp/roc/monographs/finaltce_508.pdf.


Journal Articles and Book Chapters

Ali I, Hogberg J, Hsieh JH, Auerbach S, Korhonen A, Stenius U, Silins I. Gender differences in cancer susceptibility: Role of oxidative stress. Carcinogenesis. 2016 Jul; http://dx.doi.org/10.1093/carcin/bgw076. [5]

Anderson SE, Meade BJ, Long CM, Lukomska E, Marshall NB. Investigations of immunotoxicity and allergic potential induced by topical application of triclosan in mice. J Immunotoxicol. 2016;13(2):165-172;  http://dx.doi.org/10.3109/1547691x.2015.1029146. [2]

Anderson SE, Shane H, Long C, Lukomska E, Meade BJ, Marshall NB. Evaluation of the irritancy and hypersensitivity potential following topical application of didecyldimethylammonium chloride. J Immunotoxicol. 2016 Jul;13(4):557-566; http://dx.doi.org/10.3109/1547691x.2016.1140854. [2]

Arciniega J, Wagner L, Prymula R, Sebo P, Isbrucker R, Descampe B, Chapsal JM, Costanzo A, Hendriksen C, Hoonaker M, Nelson S, Lidster K, Casey W, Allen D. Alternatives to HIST for acellular pertussis vaccines: Progress and challenges in replacement. Pharmeur Bio Sci Notes. 2016;2015:82-96; http://www.ncbi.nlm.nih.gov/pubmed/27506225. [5]

Auerbach S, Filer D, Reif D, Walker V, Holloway AC, Schlezinger J, Srinivasan S, Svoboda D, Judson R, Bucher JR, Thayer KA. Prioritizing environmental chemicals for obesity and diabetes outcomes research: A screening approach using ToxCast™ high-throughput data. Environ Health Perspect. 2016 Aug;124(8):1141-1154; http://dx.doi.org/10.1289/ehp.1510456. [5]

Auerbach SS. In vivo signatures of genotoxic and non-genotoxic chemicals In: Thomas RSW, Michael D, editors. Toxicogenomics in predictive carcinogenicity. Royal Society of Chemistry; 2016. p. 113-153. [5]

Bailey RL, Cox-Ganser JM, Duling MG, LeBouf RF, Martin SB, Jr., Bledsoe TA, Green BJ, Kreiss K. Respiratory morbidity in a coffee processing workplace with sentinel obliterative bronchiolitis cases. Am J Ind Med. 2015 Dec;58(12):1235-1245; http://dx.doi.org/10.1002/ajim.22533. [2]

Ball N, Cronin MT, Shen J, Blackburn K, Booth ED, Bouhifd M, Donley E, Egnash L, Hastings C, Juberg DR, Kleensang A, Kleinstreuer N, Kroese ED, Lee AC, Luechtefeld T, Maertens A, Marty S, Naciff JM, Palmer J, Pamies D, Penman M, Richarz AN, Russo DP, Stuard SB, Patlewicz G, van Ravenzwaay B, Wu S, Zhu H, Hartung T. Toward good read-across practice (GRAP) guidance. ALTEX. 2016;33(2):149-166; http://dx.doi.org/10.14573/altex.1601251. [5]

Bandrowski A, Brinkman R, Brochhausen M, Brush MH, Bug B, Chibucos MC, Clancy K, Courtot M, Derom D, Dumontier M, Fan LJ, Fostel J, Fragoso G, Gibson F, Gonzalez-Beltran A, Haendel MA, He YQ, Heiskanen M, Hernandez-Boussard T, Jensen M, Lin Y, Lister AL, Lord P, Malone J, Manduchi E, McGee M, Morrison N, Overton JA, Parkinson H, Peters B, Rocca-Serra P, Ruttenberg A, Sansone SA, Scheuermann RH, Schober D, Smith B, Soldatova LN, Stoeckert CJ, Taylor CF, Torniai C, Turner JA, Vita R, Whetzel PL, Zheng J. The ontology for biomedical investigations. PLoS One. 2016 Apr;11(4); http://dx.doi.org/10.1371/journal.pone.0154556. [5]

Barroso J, Ahn IY, Caldeira C, Carmichael PL, Casey W, Coecke S, Curren R, Desprez B, Eskes C, Griesinger C, Guo J, Hill E, Roi AJ, Kojima H, Li J, Lim CH, Moura W, Nishikawa A, Park H, Peng S, Presgrave O, Singer T, Sohn SJ, Westmoreland C, Whelan M, Yang X, Yang Y, Zuang V. International harmonization and cooperation in the validation of alternative methods. Adv Exp Med Biol. 2016;856:343-386; http://dx.doi.org/10.1007/978-3-319-33826-2_14. [5]

Behl M, Hsieh JH, Shafer TJ, Mundy WR, Rice JR, Boyd WA, Freedman JH, Hunter ES, III, Jarema KA, Padilla S, Tice RR. Use of alternative assays to identify and prioritize organophosphorus flame retardants for potential developmental and neurotoxicity. Neurotoxicol Teratol. 2015 Nov-Dec;52:181-193; http://dx.doi.org/10.1016/j.ntt.2015.09.003. [5]

Behl M, Rice JR, Smith MV, Co CA, Bridge M, Hsieh JH, Freedman JH, Boyd WA. Comparative toxicity of organophosphate flame retardants and polybrominated diphenyl ethers to c. Elegans. Toxicol Sci. 2016 Aug;154(2):241-252; http://dx.doi.org/10.1093/toxsci/kfw162. [5]

Bekele AZ, Gokulan K, Williams KM, Khare S. Dose and size-dependent antiviral effects of silver nanoparticles on feline calicivirus, a human norovirus surrogate. Foodborne Pathog Dis. 2016 May;13(5):239-244; http://dx.doi.org/10.1089/fpd.2015.2054. [4]

Bennett JS, Marlow DA, Nourian F, Breay J, Hammond D. Hexavalent chromium and isocyanate exposures during military aircraft painting under crossflow ventilation. J Occup Environ Hyg. 2016 May;13(5):356-371; http://dx.doi.org/10.1080/15459624.2015.1117617. [2]

Bennett WD, Ivins S, Alexis NE, Wu JH, Bromberg PA, Brar SS, Travlos G, London SJ. Effect of obesity on acute ozone-induced changes in airway function, reactivity, and inflammation in adult females. PLoS One. 2016 Aug;11(8): e0160030; [5] http://dx.doi.org/10.1371/journal.pone.0160030.

Bertke SJ, Lehman EJ, Wurzelbacher SJ, Hein MJ. Mortality of lead smelter workers: A follow‐up study with exposure assessment. Am J Ind Med. 2016;59(11):979-986; http://dx.doi.org/10.1002/ajim.22618. [2]

Bertke SJ, Meyers AR, Wurzelbacher SJ, Measure A, Lampl MP, Robins D. Comparison of methods for auto-coding causation of injury narratives. Accid Anal Prev. 2016 Mar;88:117-123; http://dx.doi.org/10.1016/j.aap.2015.12.006. [2]

Boonmuen N, Gong P, Ali Z, Chittiboyina AG, Khan I, Doerge DR, Helferich WG, Carlson KE, Martin T, Piyachaturawat P, Katzenellenbogen JA, Katzenellenbogen BS. Licorice root components in dietary supplements are selective estrogen receptor modulators with a spectrum of estrogenic and anti-estrogenic activities. Steroids. 2016 Jan;105:42-49; http://dx.doi.org/10.1016/j.steroids.2015.11.006. [4]

Boudreau MD, Imam MS, Paredes AM, Bryant MS, Cunningham CK, Felton RP, Jones MY, Davis KJ, Olson GR. Differential effects of silver nanoparticles and silver ions on tissue accumulation, distribution, and toxicity in the sprague dawley rat following daily oral gavage administration for 13 weeks. Toxicol Sci. 2016 Mar;150(1):131-160; http://dx.doi.org/10.1093/toxsci/kfv318. [3]

Boyd WA, Smith MV, Co CA, Pirone JR, Rice JR, Shockley KR, Freedman JH. Developmental effects of the ToxCast™ phase I and phase II chemicals in caenorhabditis elegans and corresponding responses in zebrafish, rats, and rabbits. Environ Health Perspect. 2016 May;124(5):586-593; http://dx.doi.org/10.1289/ehp.1409645. [5]

Boyles AL, Yetley EA, Thayer KA, Coates PM. Safe use of high intakes of folic acid: Research challenges and paths forward. Nutr Rev. 2016 Jul;74(7):469-474; http://dx.doi.org/10.1093/nutrit/nuw015. [5]

Broadwater K, de Perio MA, Roberts J, Burton NC, Lemons AR, Green BJ, Brueck SE. Investigating a persistent odor at an aircraft seat manufacturer. J Occup Env Hyg. 2016;13(10):D159-D165; http://dx.doi.org/10.1080/15459624.2016.1183017. [2]

Brown KK, Shaw PB, Mead KR, Kovein RJ, Voorhees RT, Brandes AR. Development of the chemical exposure monitor with indoor positioning (CEMWIP) for workplace VOC surveys. J Occup Environ Hyg. 2016;13(6):401-412; http://dx.doi.org/10.1080/15459624.2015.1125488. [2]

Bucher JR, Birnbaum LS. Commemorating toxicology at the National Institute of Environmental Health Sciences on the occasion of its 50th anniversary. Environ Health Perspect. 2016;124(1):A192-195. http://dx.doi.org/10.1289/EHP463. [5]

Bushel PR, Fannin RD, Gerrish K, Watkins PB, Paules RS. Blood gene expression profiling of an early acetaminophen response. Pharmacogenomics J. 2016 Mar; http://dx.doi.org/10.1038/tpj.2016.8. [5]

Camacho L, Lewis SM, Vanlandingham MM, Juliar BE, Olson GR, Patton RE, da Costa GG, Woodling K, Sepehr E, Bryant MS, Doerge DR, Basavarajappa MS, Felton RR, Delclos KB. Comparison of endpoints relevant to toxicity assessments in 3 generations of CD-1 mice fed irradiated natural and purified ingredient diets with varying soy protein and isoflavone contents. Food Chem Toxicol. 2016 Aug;94:39-56; http://dx.doi.org/10.1016/j.fct.2016.05.014. [3]

Carbone M, Kanodia S, Chao A, Miller A, Wali A, Weissman D, Adjei A, Baumann F, Boffetta P, Buck B, de Perrot M, Dogan AU, Gavett S, Gualtieri A, Hassan R, Hesdorffer M, Hirsch FR, Larson D, Mao W, Masten S, Pass HI, Peto J, Pira E, Steele I, Tsao A, Woodard GA, Yang H, Malik S. Consensus report of the 2015 Weinman International Conference on Mesothelioma. J Thorac Oncol. 2016 Aug;11(8):1246-1262; http://dx.doi.org/10.1016/j.jtho.2016.04.028. [5]

Carlin DJ, Naujokas MF, Bradham KD, Cowden J, Heacock M, Henry HF, Lee JS, Thomas DJ, Thompson C, Tokar EJ, Waalkes MP, Birnbaum LS, Suk WA. Arsenic and environmental health: State of the science and future research opportunities. Environ Health Perspect. 2016 Jul;124(7):890-899; http://dx.doi.org/10.1289/ehp.1510209. [5]

Casey WM. Advances in the development and validation of test methods in the United States. Toxicol Res. 2016 Jan;32(1):9-14; http://dx.doi.org/10.5487/tr.2016.32.1.009. [5]

Castro L, Gao X, Moore AB, Yu L, Di X, Kissling GE, Dixon D. A high concentration of genistein induces cell death in human uterine leiomyoma cells by autophagy. Expert Opin Environ Biol. 2016 May;5(Suppl 1); http://dx.doi.org/10.4172/2325-9655.s1-003. [5]

Ceballos DM, Whittaker SG, Lee EG, Roberts J, Streicher R, Nourian F, Gong W, Broadwater K. Occupational exposures to new dry cleaning solvents: High-flashpoint hydrocarbons and butylal. J Occup Env Hyg. 2016 Oct;13(10):759-769; http://dx.doi.org/10.1080/15459624.2016.1177648. [2]

Cena L, Chen T, Keane M. Evolution of welding-fume aerosols with time and distance from the source: A study was conducted on the spatiotemporal variability in welding-fume concentrations for the characterization of first- and second-hand exposure to welding fumes. Weld J. 2016 Aug;95(Suppl):280s-285s. [2]

Cerniglia CE, Pineiro SA, Kotarski SF. An update discussion on the current assessment of the safety of veterinary antimicrobial drug residues in food with regard to their impact on the human intestinal microbiome. Drug Test Anal. 2016 May;8(5-6):539-548; http://dx.doi.org/10.1002/dta.2024. [4]

Chalbot MCG, Chitranshi P, Gamboa da Costa G, Pollock E, Kavouras IG. Characterization of water-soluble organic matter in urban aerosol by 1H-NMR spectroscopy. Atmos Environ. 2016 Mar;128:235-245; http://dx.doi.org/10.1016/j.atmosenv.2015.12.067. [4]

Chappell G, Pogribny IP, Guyton KZ, Rusyn I. Epigenetic alterations induced by genotoxic occupational and environmental human chemical carcinogens: A systematic literature review. Mutat Res Rev Mutat Res. 2016 Apr-Jun;768:27-45; http://dx.doi.org/10.1016/j.mrrev.2016.03.004. [4]

Chappell G, Silva GO, Uehara T, Pogribny IP, Rusyn I. Characterization of copy number alterations in a mouse model of fibrosis-associated hepatocellular carcinoma reveals concordance with human disease. Cancer Med. 2016 Mar;5(3):574-585; http://dx.doi.org/10.1002/cam4.606. [4]

Chen S, Zhang Z, Qing T, Ren Z, Yu D, Couch L, Ning B, Mei N, Shi L, Tolleson WH, Guo L. Activation of the Nrf2 signaling pathway in usnic acid-induced toxicity in HepG2 cells. Arch Toxicol. 2016; http://dx.doi.org/10.1007/s00204-016-1775-y. [4]

Chen T, Schwegler-Berry D, Cumpston A, Cumpston J, Friend S, Stone S, Keane M. Performance of a scanning mobility particle sizer in measuring diverse types of airborne nanoparticles: Multi-walled carbon nanotubes, welding fumes, and titanium dioxide spray. J Occup Environ Hyg. 2016 Jul;13(7):501-518; http://dx.doi.org/10.1080/15459624.2016.1148267. [2]

Churchill SR, Morgan DL, Kissling GE, Travlos GS, King-Herbert AP. Impact of environmental enrichment devices on NTP in vivo studies. Toxicol Pathol. 2016 Jan;44(2):233-245; http://dx.doi.org/10.1177/0192623315625330. [5]

Cimino AM, Boyles AL, Thayer KA, Perry MJ. Effects of neonicotinoid pesticide exposure on human health: A systematic review. Environ Health Perspect. 2016 Jul; http://dx.doi.org/10.1289/ehp515. [5]

Clippinger AJ, Ahluwalia A, Allen D, Bonner JC, Casey W, Castranova V, David RM, Halappanavar S, Hotchkiss JA, Jarabek AM, Maier M, Polk W, Rothen-Rutishauser B, Sayes CM, Sayre P, Sharma M, Stone V. Expert consensus on an in vitro approach to assess pulmonary fibrogenic potential of aerosolized nanomaterials. Arch Toxicol. 2016 Jul;90(7):1769-1783; http://dx.doi.org/10.1007/s00204-016-1717-8. [5]

Coelho SG, Patri AK, Wokovich AM, McNeil SE, Howard PC, Miller SA. Repetitive application of sunscreen containing titanium dioxide nanoparticles on human skin. JAMA Dermatol. 2016 Apr;152(4):470-472; http://dx.doi.org/10.1001/jamadermatol.2015.5944. [4]

Cooper GS, Lunn RM, Agerstrand M, Glenn BS, Kraft AD, Luke AM, Ratcliffe JM. Study sensitivity: Evaluating the ability to detect effects in systematic reviews of chemical exposures. Environ Int. 2016 Jul-Aug;92-93:605-610; http://dx.doi.org/10.1016/j.envint.2016.03.017. [5]

Cote I, Andersen ME, Ankley GT, Barone S, Birnbaum LS, Boekelheide K, Bois FY, Burgoon LD, Chiu WA, Crawford-Brown D, Crofton KM, DeVito M, Devlin RB, Edwards SW, Guyton KZ, Hattis D, Judson RS, Knight D, Krewski D, Lambert J, Maull EA, Mendrick D, Paoli GM, Patel CJ, Perkins EJ, Poje G, Portier CJ, Rusyn I, Schulte PA, Simeonov A, Smith MT, Thayer KA, Thomas RS, Thomas R, Tice RR, Vandenberg JJ, Villeneuve DL, Wesselkamper S, Whelan M, Whittaker C, White R, Xia M, Yauk C, Zeise L, Zhao J, DeWoskin RS. The next generation of risk assessment multiyear study- highlights of findings, applications to risk assessment and future directions. Environ Health Perspect. 2016 Apr; http://dx.doi.org/10.1289/ehp233. [5]

Croston TL, Nayak AP, Lemons AR, Goldsmith WT, Gu JK, Germolec DR, Beezhold DH, Green BJ. Influence of Aspergillus fumigatus conidia viability on murine pulmonary microRNA and mRNA expression following subchronic inhalation exposure. Clin Exp Allergy. 2016;46(10):1315-1327; http://dx.doi.org/10.1111/cea.12783. [1,5]

Cruz-Topete D, Myers PH, Foley JF, Willis MS, Cidlowski JA. Corticosteroids are essential for maintaining cardiovascular function in male mice. Endocrinology. 2016 Jul;157(7):2759-2771; http://dx.doi.org/10.1210/en.2015-1604. [5]

Cummings KJ, Virji MA, Park JY, Stanton ML, Edwards NT, Trapnell BC, Carey B, Stefaniak AB, Kreiss K. Respirable indium exposures, plasma indium, and respiratory health among indium-tin oxide (ITO) workers. Am J Ind Med. 2016 Jul;59(7):522-531; http://dx.doi.org/10.1002/ajim.22585. [2]

Daniels RD, Bertke S, Dahm MM, Yiin JH, Kubale TL, Hales TR, Baris D, Zahm SH, Beaumont JJ, Waters KM, Pinkerton LE. Exposure-response relationships for select cancer and non-cancer health outcomes in a cohort of U.S. firefighters from San Francisco, Chicago and Philadelphia (1950-2009). Occup Environ Med. 2015 Oct;72(10):699-706; http://dx.doi.org/10.1136/oemed-2014-102671. [2]

Davidson D, Derk R, He X, Stueckle T, Cohen J, Pirela S, Demokritou P, Rojanasakul Y, Rojanasakul L. Direct stimulation of human fibroblasts by nCeO2 in vitro is attenuated with an amorphous silica coating. Part Fibre Toxicol. 2016 May;13(23):1-14; http://dx.doi.org/10.1186/s12989-016-0134-8. [2]

DeBord DG, Burgoon L, Edwards SW, Haber LT, Kanitz MH, Kuempel E, Thomas RS, Yucesoy B. Systems biology and biomarkers of early effects for occupational exposure limit setting. J Occup Env Hyg. 2015;Suppl1:12:S41-S54; http://dx.doi.org/10.1080/15459624.2015.1060324. [2]

DeBord DG, Carreón T, Lentz TJ, Middendorf PJ, Hoover MD, Schulte PA. Use of the "exposome" in the practice of epidemiology: A primer on -omic technologies. Am J Epidemiol. 2016 Aug;184(4):302-314; http://dx.doi.org/10.1093/aje/kwv325. [2]

Dennis KK, Auerbach SS, Balshaw DM, Cui Y, Fallin MD, Smith MT, Spira A, Sumner S, Miller GW. The importance of the biological impact of exposure to the concept of the exposome. Environ Health Perspect. 2016;124(10):1504-1510. http://dx.doi.org/10.1289/ehp140. [5]

DeWitt JC, Germolec DR, Luebke RW, Johnson VJ. Associating changes in the immune system with clinical diseases for interpretation in risk assessment. Curr Protoc Toxicol. 2016;67:18.1.1-18.1.22; http://dx.doi.org/10.1002/0471140856.tx1801s67. [5]

Ding W, Bishop ME, Lyn-Cook LE, Davis KJ, Manjanatha MG. In vivo alkaline comet assay and enzyme-modified alkaline comet assay for measuring DNA strand breaks and oxidative DNA damage in rat liver. J Vis Exp. 2016 May;(111): e53833; http://dx.doi.org/10.3791/53833. [4]

Dinse GE, Jusko TA, Whitt IZ, Co CA, Parks CG, Satoh M, Chan EKL, Rose KM, Walker NJ, Birnbaum LS, Zeldin DC, Weinberg CR, Miller FW. Associations between selected xenobiotics and antinuclear antibodies in the National Health and Nutrition Examination Survey, 1999-2004. Environ Health Perspect. 2016 Apr;124(4):426-436; http://dx.doi.org/10.1289/ehp.1409345. [5]

Doerge DR, Woodling KA, Churchwell MI, Fleck SC, Helferich WG. Pharmacokinetics of isoflavones from soy infant formula in neonatal and adult rhesus monkeys. Food Chem Toxicol. 2016 Jun;92:165-176; http://dx.doi.org/10.1016/j.fct.2016.04.005. [4]

Dong J, Ma Q. In vivo activation of a T helper 2-driven innate immune response in lung fibrosis induced by multi-walled carbon nanotubes. Arch Toxicol. 2016 Sep;90(9):2231-2248; http://dx.doi.org/10.1007/s00204-016-1711-1. [2]

Dong J, Ma Q. Suppression of basal and carbon nanotube-induced oxidative stress, inflammation and fibrosis in mouse lungs by Nrf2. Nanotoxicology. 2016 Aug;10(6):699-709; http://dx.doi.org/10.3109/17435390.2015.1110758. [2]

Duan P, Fisher JW, Yoshida K, Zhang L, Burckart GJ, Wang J. Physiologically based pharmacokinetic prediction of linezolid and emtricitabine in neonates and infants. Clin Pharmacokinet. 2016:1-12; http://dx.doi.org/10.1007/s40262-016-0445-9. [4]

Duggirala HJ, Tonning JM, Smith E, Bright RA, Baker JD, Ball R, Bell C, Bright-Ponte SJ, Botsis T, Bouri K, Boyer M, Burkhart K, Condrey GS, Chen JJ, Chirtel S, Filice RW, Francis H, Jiang H, Levine J, Martin D, Oladipo T, O'Neill R, Palmer LA, Paredes A, Rochester G, Sholtes D, Szarfman A, Wong HL, Xu Z, Kass-Hout T. Use of data mining at the Food and Drug Administration. J Am Med Inform Assoc. 2016 Mar;23(2):428-434; http://dx.doi.org/10.1093/jamia/ocv063. [4]

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[1] Funded by the NIEHS/NIOSH Interagency Agreement

[2] Funded by NIOSH voluntary allocations to the NTP

[3] Funded by the NIEHS/NCTR Interagency Agreement

[4] Funded by NCTR voluntary allocations to the NTP

[5] Funded by NIEHS voluntary allocations to the NTP