NTP Logo

Annual Report for Fiscal Year 2016

Annual Report for Fiscal Year 2016
Menu
https://ntp.niehs.nih.gov/go/807201

Nominations

NTP continually accepts and reviews nominations for studies in its research and testing program. The NTP nomination process is open to the public, and nominations can be submitted via the NTP website. Agencies represented on the NTP Executive Committee also identify and forward nominations to NTP.

For new studies or research projects of substantial scope and complexity, NTP research concepts or project plans are prepared to facilitate external review as part of a multi-step process with input from NTP participating federal agencies, Board of Scientific Counselors, and the public. In addition to new research programs, NTP also conducts targeted studies to extend or explain findings observed in previously conducted studies and address nominations that are closely aligned with current research efforts.

In November 2015, the California Office of Environmental Health Hazard Assessment nominated synthetic turf/recycled tire crumb rubber as part of its Environmental Health Study of Synthetic Turf. In response, NTP formulated plans to conduct a number of studies to enhance the understanding of potential health impacts of chemicals released from synthetic turf with an emphasis on the crumb rubber. The NTP presented the proposed research program to the Board of Scientific Counselors in June 2016.

Also in FY 2016, in response to a nomination from the Environmental Protection Agency’s Office of Land and Emergency Management, NTP formulated plans to evaluate the potential for water-soluble thallium compounds to induce neurological, reproductive, and developmental toxicity following subchronic exposure in rodents. The NTP Research Concept was released and presented to the Board of Scientific Counselors in June 2016

Questions about the nomination, review, and selection process can be sent to Scott Masten, Ph.D.

Research and Testing Projects Initiated in FY 2016

Project
CASRN*
Study Scientist
Nomination Rationale and Project Aims
Synthetic Turf/Recycled Tire Crumb Rubber
N/A

Roberts
In recent years, public health concern for playing on synthetic turf fields has increased. Crumb rubber, manufactured from recycled tires and used in synthetic turf and playground mats, contains numerous potential carcinogenic and toxic substances. The NTP research program is considering potential routes of human contact with crumb rubber and aims to understand what exposure conditions in an experimental laboratory setting have the potential to impact the risk of developing adverse health outcomes.

Thallium and Thallium Salts:

  • Metallic Thallium (TI); 7440-28-0
  • Thallium (I) Acetate; 563-68-8
  • Thallium (I) Carbonate; 6533-73-9
  • Thallium (I) Chlorate; 13453-30-0
  • Thallium (I) Chloride; 7791-12-0
  • Thallium (I) Nitrate; 10102-45-1
  • Thallium (I) Oxide; 1314-12-1
  • Thallium (III) Oxide; 1314-32-5
  • Thallium Selenide; 15123-92-9
  • Thallium Sulfate; 7446-18-6

Shipkowski

Potential for widespread human exposure to thallium exists primarily due to its presence as a contaminant in drinking water near hazardous waste and industrial sites, and from instances of accidental or deliberate poisoning. There is a lack of adequate data to support risk evaluations for human health following thallium exposure. The goal of this research program is to evaluate the potential for water-soluble thallium compounds to induce neurological, reproductive, and developmental toxicity following subchronic exposure in rodents.

*CASRN = Chemical Abstracts Service Registry Number