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Annual Report for Fiscal Year 2016

Annual Report for Fiscal Year 2016
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https://ntp.niehs.nih.gov/go/807136

Genetic Toxicity

Genetic toxicity test results are used to help interpret general toxicity, carcinogenicity, or other in vivo test results, and provide a database for use in structure-activity relationship analysis. Substances tested for genetic toxicity during FY 2016 are listed in the table below.

Genetic Toxicity Studies During FY 2016

Test Article CASRN* Species Testing Battery Status
Aspergillus fumigatus mold N/A Mice Micronucleus  Completed
Black cohosh 84776-26-1 Salmonella Salmonella  Completed
N-Butyl glycidyl ether 2426-08-6 Mice Micronucleus  Ongoing
N-Butyl glycidyl ether 2426-08-6 Rats Micronucleus  Ongoing
N-Butylpyridinium chloride 1124-64-7 Rats Micronucleus  Completed
Corn oil 8001-30-7 Rats Micronucleus  Completed
2,2'-Dimorpholinodiethyl ether 6425-39-4 Salmonella  Salmonella  Ongoing
Echinacea purpurea extract 90028-20-9 Salmonella Salmonella  Completed
Echinacea purpurea extract 90028-20-9 Salmonella Salmonella  Completed
Echinacea purpurea extract 90028-20-9 Salmonella Salmonella  Completed
Echinacea purpurea extract 90028-20-9 Salmonella Salmonella  Completed
Echinacea purpurea extract 90028-20-9 Salmonella Salmonella  Completed
Echinacea purpurea extract 90028-20-9 Salmonella Salmonella  Completed
Echinacea purpurea extract 90028-20-9 Salmonella Salmonella  Completed
Echinacea purpurea extract 90028-20-9 Salmonella Salmonella  Completed
2-Nitro-2-ethyl-1,3-propanediol 597-09-1 Salmonella Salmonella  Completed
Perfluorodecanoic acid 335-76-2 Rats Micronucleus  Completed
Sulfolane 126-33-0 Rats Micronucleus  Ongoing
Sulfolane 126-33-0 Mice Micronucleus  Ongoing
Vinpocetine 42971-09-5 Mice Micronucleus  Ongoing
Vinpocetine 42971-09-5 Mice Micronucleus  Ongoing
Zinc carbonate, basic 5263-02-5 Rats Micronucleus  Completed
Zinc carbonate, basic 5263-02-5 Rats Micronucleus  Completed
Zinc carbonate, basic 5263-02-5 Rats Micronucleus  Completed
Zinc carbonate, basic 5263-02-5 Rats Micronucleus  Completed
*CASRN = Chemical Abstracts Service Registry Number