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Annual Report for Fiscal Year 2016

Annual Report for Fiscal Year 2016
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https://ntp.niehs.nih.gov/go/807082

Project Review Committee Approved

The table below lists studies that were approved by either the internal NIEHS/NTP protocol approval committee or the internal NIEHS/NTP project review committee, but were not started during FY 2016.

Protocol Title Study Scientist
Developmental immunotoxicology evaluation of bisphenol AF in harlan sprague dawley rats exposed via dosed feed Germolec/Sutherland
Three-month toxicity studies of 1,2,4-trimethylbenzene in harlan sprague dawley rats (after prenatal exposure, including selected reproductive, developmental, and neurotoxicity endpoints) and B6C3F1/N mice exposed via whole body inhalation Roberts
Developmental immunotoxicity evaluation of tris(chloropropyl) phosphate (TCPP) in harlan sprague dawley rats exposed via dosed feed Germolec/Ryan
Subchronic toxicity of sodium metavanadate and vanadyl sulfate in harlan sprague dawley rats (after perinatal exposure) and B6C3F1/N mice exposed via dosed drinking water Roberts
Immunotoxicology screening study of Echinacea purpurea root extract in female harlan sprague dawley rats exposed via oral gavage Ryan
Toxicokinetic studies of phenolic benzotriazole class chemicals (PBTZs) in male harlan sprague dawley rats via gavage and intravenous administration Waidyanatha/Blystone
Immunotoxicology screening study of sodium metavanadate in female B6C3F1/N mice exposed via drinking water Roberts
Prenatal developmental dose range-finding toxicity study of the fixed-dose ratio tri-combination (1:1.5:3) of emtricitabine, tenofovir disoproxil fumarate, and efavirenz in CD-1 mice exposed via gavage McIntyre
Preliminary toxicokinetic investigation in pregnant CD-1 mice treated via gavage with either emtricitabine, tenofovir disoproxil fumarate, efavirenz; or the fixed-dose ratio tricombination (1:1.5:3)  McIntyre
Immunological evaluation of acenaphthenequinone, dibenzothiophene, and pyrene in B6C3F1/N mice treated for 28 days via gavage: polycyclic aromatic hydrocarbon mixtures assessment program (PAC-MAP) studies Germolec/Rider
Absorption, distribution, metabolism, and excretion (ADME) of triclocarban in harlan sprague dawley rats and B6C3F1/N mice following gavage, intravenous administration, and dermal application of [14C]triclocarban Waidyanatha/Sutherland
Toxicokinetic studies of bisphenol S in harlan sprague dawley rats and B6C3F1/N mice following gavage, intravenous, and feed exposure  Waidyanatha/Sutherland
Prenatal toxicity study of 2-{[1-(4-phenoxyphenoxy)propan-2-yl]oxy}pyridine in harlan sprague dawley rats exposed via gavage McIntyre
Immunotoxicity of 2-­{[1-­(4-­phenoxyphenoxy)propan-­2-­yl]oxy}pyridine in sprague dawley rats exposed via gavage Germolec
Perinatal dose range-finding study of thallium sulfate in sprague dawley rats and 14-day toxicity study of thallium sulfate in B6C3F1/N mice exposed via dosed drinking water Shipkowski
Immunotoxicity of N-butylbenzenesulfonamide in B6C3F1/N mice exposed for 28 days via dosed feed Frawley/Rider