NTP Logo

Annual Report for Fiscal Year 2017

Annual Report for Fiscal Year 2017
Menu
https://ntp.niehs.nih.gov/go/837910

NTP's Public Health Impact on Regulatory Agencies

Federal and state regulatory agencies use NTP study data and recommendations in considering the need to regulate and test specific chemicals for the protection of human health. The NTP data and recommendations used by other agencies in FY 2017 are listed below. A full listing is available on the NTP website.

Use of NTP Study Data or Recommendations by Federal and State Regulatory Agencies in FY 2017

Notice Summary of Notice NTP Information Cited

Chemical Listed as Known to the State of California to Cause Cancer: Pentabromodiphenyl Ether Mixture [DE-71 (technical grade)]

[Effective Date: July 7, 2017]

The California Office of Environmental Health Hazard Assessment (OEHHA) added pentabromodiphenyl ether mixture [DE-71 (technical grade)] to the list of chemicals known to cause cancer under the "authoritative bodies" mechanism.

July 7, 2017 -- Proposition 65

The listing of pentabromodiphenyl ether mixture [DE-71 (technical grade)] is based on formal identification by the NTP, an authoritative body, that the chemical causes cancer. (see NTP Technical Report 589).

Notice of Amendment to Section 25705, No Significant Risk Level for Styrene

[Effective Date: July 1, 2017]

On May 4, 2017, the Office of Administrative Law approved the amendment of Title 27, California Code of Regulations, section 25705, No Significant Risk Level (NSRL) to establish a No Significant Risk Level of 27 micrograms per day for the chemical styrene.

May 11, 2017 -- Proposition 65

NTP (2011). Report on Carcinogens, 12th Edition, U.S. Department of Health and Human Services, Public Health Service, NTP, Research Triangle Park, North Carolina. NTP is designated an authoritative body for identifying chemicals that cause cancer.

Amendment to Section 25805, Maximum Allowable Dose Level (Oral) for Ethylene Glycol (Ingested)

[Effective Date: July 1, 2017]

On April 4, 2017, the Office of Administrative Law approved the amendment of Title 27, California Code of Regulations, section 25805, Maximum Allowable Dose Level (MADL) to establish a MADL of 8,700 (oral) micrograms per day for the chemical ethylene glycol (ingested).

April 6, 2017 -- Proposition 65

NTP (2004). NTP-CERHR Monograph on the Potential Human Reproductive and Developmental Effects of Ethylene Glycol. NTP CERHR MON. 2004 Jan;(11):1-III36. PubMed PMID: 16015391.

Final Rule: Oxytetracycline; Pesticide Tolerances for Emergency Exemptions

This regulation establishes a time-limited tolerance for residues of oxytetracycline in or on fruit, citrus, or crop group 10-10. This action, in response to the Environmental Protection Agency’s (EPA’s) granting of an emergency exemption for the use of oxytetracycline in or on fruit, citrus, or crop group 10-10 under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) authorizing use of the pesticide in citrus production, established a time-limited maximum permissible level for residues of oxytetracycline in or on commodities in this crop group. The time-limited tolerance expires on December 31, 2019.

March 10, 2017 -- 82 FR 13245

Based upon a literature search of toxicity in animals and the weight of the evidence as a whole, EPA has classified oxytetracycline as a "Group D" carcinogen ("Not Classifiable as to Human Carcinogenicity"). A review of the same animal toxicity data by the NTP Peer Review Committee was in agreement with this classification. Therefore, a dietary exposure assessment for the purpose of assessing cancer risk is unnecessary and was not conducted (see NTP Technical Report 315).

Final Rule: Formaldehyde Emission Standards for Composite Wood Products

EPA issued a final rule to implement the Formaldehyde Standards for Composite Wood Products Act, which added Title VI to the Toxic Substances Control Act (TSCA). The purpose of TSCA Title VI is to reduce formaldehyde emissions from composite wood products, which will reduce exposures to formaldehyde and result in benefits from avoided adverse health effects. This final rule also establishes a third-party certification program for hardwood plywood, medium-density fiberboard, and particleboard and includes procedures for the accreditation of third-party certifiers and general requirements for accreditation bodies and third-party certifiers.

December 12, 2016 -- 81 FR 89674

NTP (2014). Report on Carcinogens, 13th Edition, U.S. Department of Health and Human Services, Public Health Service, NTP, Research Triangle Park, North Carolina. NTP is designated an authoritative body for identifying chemicals that cause cancer.

Chemical Listed as Known to the State of California to Cause Cancer: Pentachlorophenol and By-Products of its Synthesis (Complex Mixture)

[Effective Date: October 21, 2016]

Effective October 21, 2016, OEHHA is adding pentachlorophenol and by-products of its synthesis (complex mixture) to the list of chemicals known to the state to cause cancer.

October 21, 2016 -- Proposition 65

NTP (2014). Report on Carcinogens, 13th Edition, U.S. Department of Health and Human Services, Public Health Service, NTP, Research Triangle Park, North Carolina. NTP is designated an authoritative body for identifying chemicals that cause cancer.

*CASRN = Chemical Abstracts Service Registry Number