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Annual Report for Fiscal Year 2018

Annual Report for Fiscal Year 2018

Letter From the NIEHS and NTP Director

In fiscal year (FY) 2018, NTP continued to advance toxicology and inform public health policy by providing information to decision makers and the public about substances in our environment. Numerous studies were published on substances of public health concern, such as flame retardants, cell phone radiofrequency radiation, and widely used industrial chemicals. Among these is the final report from the CLARITY-BPA core study and data sets from CLARITY-BPA grantee studies to evaluate the range of potential health effects from BPA in rats.

In addition, NTP engaged in several activities to advance alternatives to animal testing. Particularly noteworthy was publication of the Strategic Roadmap for Establishing New Approaches to Evaluate the Safety of Chemicals and Medical Products in the United States, a consensus perspective developed with input from many groups. The “Tox21” consortium met to discuss the new Toxicology in the 21st Century (Tox21) strategic plan that will continue to refine prediction of chemical toxicity to humans.

NTP continued its systemic review literature activities to identify potential hazards for human health. In partnership with the NIH Countermeasures Against Chemical Threats (CounterACT) Program, NTP conducted a systematic review to assess long-term neurological effects following acute exposure to the organophosphorus nerve agent sarin. Antimony trioxide and Helicobacter pylori were evaluated for possible listing in the congressionally mandated Report on Carcinogens.

I invite you to read this report to learn about what we accomplished in FY 2018 toward advancing toxicology and safeguarding public health by generating and communicating trusted scientific information

Linda S. Birnbaum, Ph.D., D.A.B.T., A.T.S.

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Dr. Linda Birnbaum

Dr. Birnbaum has served as the Director of the National Institute of Environmental Health Sciences (NIEHS) and the National Toxicology Program (NTP) since 2009. (Photo courtesy of Steve McCaw)