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Annual Report for Fiscal Year 2018

Annual Report for Fiscal Year 2018


Toxicology in the 21st Century (Tox21) is a unique federal collaboration among the National Institutes of Health (NIH), including the National Toxicology Program (NTP) at the National Institute of Environmental Health Sciences (NIEHS) and the National Center for Advancing Translational Sciences (NCATS), Environmental Protection Agency (EPA), and U.S. Food and Drug Administration (FDA). Its purpose is to develop new methods to rapidly test whether chemicals adversely affect human health. Tox21 uses robotic, high-throughput screening methods and other testing approaches to evaluate large numbers of chemicals quickly and efficiently to provide insight into potential human health effects. Bioinformatics and computational toxicology support for Tox21 is provided by Tox21 members, including members of the Biomolecular Screening Branch and the NTP Interagency Center for the Evaluation of Alternative Toxicological Methods.

NTP Tox21 projects in FY 2018 were carried out by the NIEHS/NTP staff listed below.