The Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM) is a permanent interagency committee of NIEHS under NICEATM. Established by the ICCVAM Authorization Act of 2000 (42 U.S.C. 285l-3), its purpose is “to establish, wherever feasible, guidelines, recommendations, and regulations that promote the regulatory acceptance of new or revised scientifically valid toxicological tests that protect human and animal health and the environment while reducing, refining, or replacing animal tests and ensuring human safety and product effectiveness.”
ICCVAM is composed of representatives from 16 U.S. federal regulatory and research agencies that generate or use toxicological and safety testing information (see below). Warren Casey, Ph.D., serves as administrative director of ICCVAM.
Related Annual Report Pages:
Strategic Roadmap for New Approaches to Evaluate the Safety of Chemicals and Medical Products
ICCVAM Test Method Evaluation Activities
ICCVAM International Validation Activities