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Annual Report for Fiscal Year 2018

Annual Report for Fiscal Year 2018


The Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM) is a permanent interagency committee of NIEHS under NICEATM. Established by the ICCVAM Authorization Act of 2000 (42 U.S.C. 285l-3), its purpose is “to establish, wherever feasible, guidelines, recommendations, and regulations that promote the regulatory acceptance of new or revised scientifically valid toxicological tests that protect human and animal health and the environment while reducing, refining, or replacing animal tests and ensuring human safety and product effectiveness.”

ICCVAM is composed of representatives from 16 U.S. federal regulatory and research agencies that generate or use toxicological and safety testing information (see below). Warren Casey, Ph.D., serves as administrative director of ICCVAM.

  • Agency for Toxic Substances and Disease Registry
  • U.S. Consumer Product Safety Commission
  • U.S. Department of Agriculture
  • U.S. Department of Defense
  • U.S. Department of Energy
  • U.S. Department of the Interior
  • U.S. Department of Transportation
  • U.S. Environmental Protection Agency
  • U.S. Food and Drug Administration
  • National Cancer Institute
  • National Institute of Environmental Health Sciences
  • National Institutes of Health
  • National Institute for Occupational Safety and Health
  • National Institutes of Standards and Technology
  • National Library of Medicine
  • Occupational Safety and Health Administration

Related Annual Report Pages:
Strategic Roadmap for New Approaches to Evaluate the Safety of Chemicals and Medical Products
ICCVAM Meetings
ICCVAM Test Method Evaluation Activities
ICCVAM International Validation Activities