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https://ntp.niehs.nih.gov/go/COC

Workshop: Converging on Cancer

converging on cancer workshop

April 29-30, 2019
9 a.m. - 5 p.m. EDT
Location: William Jefferson Clinton East Building
U.S. Environmental Protection Agency, Washington, D.C.

Cancer is a leading cause of mortality worldwide. While the defining feature of cancer is uncontrolled division of abnormal cells, it is a complex disease with varied presentations (i.e., different etiologies and target tissues) that involves dysregulation of multiple interconnected signaling pathways. Diverse environmental factors have been associated with the development and progression of various cancer types. A critical question in the field of environmental health is how to harness what is known about cancer biology and associated environmental exposures to improve public health outcomes. The Converging on Cancer Workshop is aimed at providing a clear path forward for evaluating the interactions between environmental exposures and cancer biology using the latest tools in toxicology and identifying knowledge gaps that require research attention. Potential applications of this understanding include building a framework for incorporating mechanistic data into cancer risk assessment, developing effective screening tools to detect the carcinogenic potential of environmental chemicals (including mixtures), engineering safer products, and designing more effective multi-target therapeutics. 

This free meeting is open to the public with attendance limited only by the space available. The meeting will consist of plenary sessions which will be webcast, breakout discussion sessions, and a poster session. The plenary sessions will be webcast but the breakout sessions and poster session will not be webcast.

Pre-Workshop Webinars

Prior to the Workshop, NTP held two informational webinars. The purpose of the webinars was to provide background information to workshop participants and facilitate productive discussions during the workshop. Registration for the Converging on Cancer Workshop (in person or webcast) was required for access to the pre-workshop webinars. The webinar dates and topics were:

  • April 17, 2019, 1-2 pm (Eastern): Cynthia Rider (NIEHS/NTP) “The Path to Converging on Cancer” and Glenn Rice (US EPA) “Cancer Risk Assessment for Chemical Mixtures at US EPA”
  • April 22, 2019, 12-1 pm (Eastern): Warren Casey (NIEHS/NTP) “Carcinogenicity Health Effects Innovation: Modernizing the NTP Approach for Assessing Carcinogenic Risk from Environmental Exposures” and Mark Fielden (Amgen) “The Key Characteristics of Carcinogens: Integration with the Hallmarks of Cancer and Assays and Biomarkers to Measure Them” [View Video]

Request for Information (RFI) Input on Assays and Approaches for Evaluating Chemical Effects on Cancer Pathways 

Federal Register notice (PDF HTML)

Agenda

Flyer

Poster Abstracts

Presentations

Post Workshop Update

Note: Individuals with disabilities who need accommodation must request it at least five business days prior to the meeting. TTY users should contact the Federal TTY Relay Service at 800-877-8339. Otherwise, contact Dr. Rider for assistance.

Contact information

For questions or additional information contact: