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Nomination Summary for Aluminum contaminants of drinking water (N20025)

Nominated Substances: Aluminum citrate, Aluminum fluoride

Nomination Date: 02/04/2000

Nominator: NIEHS, EPA

Rationale: Aluminum is a listed by the EPA as a drinking water contaminant with a high health research priority. Since aluminum is found in nearly all drinking water and fluoridation may enhance absorption, there is a need for long-term low concentration rodent studies. The effects of aluminum citrate & aluminum fluoride complexes on body burdens of aluminum including the brain need to be evaluated.

NTP Principles: 1, 2

Agents and Status

The following information relates to the specific agent and may include history from earlier or later nominations for this same agent.

CASRN: 31142-56-0

Agent Name: Aluminum citrate

CASRN: 7784-18-1

Agent Name: Aluminum fluoride