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Nominated Substances: Bilberry fruit extract
Nomination Date: 05/31/2000
Nominator: NCI
Rationale: Bilberry fruit extract, a popular dietary supplement, was nominated based on its widespread use for eye strain and other eye problems. No information on the effects of long-term administration of bilberry or its anthocyanosides was found. Marginal genotoxic activity is predicted on the basis of structural analysis of flavonoids.