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Nomination Summary for 2-Methoxy-4-nitroaniline (N20613)

Nominated Substances: 2-Methoxy-4-nitroaniline

Nomination Date: 04/26/2006

Nominator: NCI

Rationale: It is used in dyeing textiles, as a dye in the printing industry, and as an intermediate in the synthesis of Azo dyes in tattoo inks, emulsion paints and toy enamels. Given the concerns about other anisidines, findings that this agent is mutagenic when metabolically activated raises concerns about the carcinogenic potential of this compound.

NTP Principles: 1, 6, 7

Agents and Status

The following information relates to the specific agent and may include history from earlier or later nominations for this same agent.

CASRN: 97-52-9

Agent Name: 2-Methoxy-4-nitroaniline