An official website of the United States government
The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.
The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Nominated Substances: Estragole
Nomination Date: 09/00/1979
Nominator: NCI
Rationale: Nominated due to its structural similarity to the known carcinogen, safrole, and preliminary carcinogenicity studies in which it induced significant incidences of hepatocellular carcinomas in preweanling mice following subcutaneous injections. Estragole has the potential for wide-spread human exposure since it is used as a food flavoring agent and as a fragrance.