An official website of the United States government
The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.
The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Nominated Substances: Cimetidine
Nomination Date: 03/11/1991
Nominator: Private Individual
Rationale: This commonly used gastric acid inhibitor appears to increase SCE frequency in ulcer patients and following in-vitro incubation of human lymphocytes. It also produces chromosomal aberrations in rodent models. Inadequate testing for carcinogenicity.
NTP Principles: not specified