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Nomination Summary for Brominated chemicals (N95034)

Nominated Substances: Bromoacetic acid, Bromochloromethane, 2-Bromo-2-nitro-1,3-propanediol, Bromoxynil octanoate, 1,2-Dibromo-2,4-dicyanobutane, Tetrabromophthalic anhydride, 2,4,6-Tribromophenol, Tribromosalan

Nomination Date: 07/31/1995

Nominator: NIEHS

Rationale: Most brominated chemicals evaluated to-date by the NTP were carcinogenic in rodents. The mechanisms of carcinogenesis are unknown. Three of the nominated brominated chemicals have high production volumes and were identified as hazardous substances. Five of the brominated chemicals were identified as pesticides that are regulated by the EPA.

NTP Principles: not specified

Agents and Status

The following information relates to the specific agent and may include history from earlier or later nominations for this same agent.

CASRN: 79-08-3

Agent Name: Bromoacetic acid

CASRN: 74-97-5

Agent Name: Bromochloromethane

CASRN: 52-51-7

Agent Name: 2-Bromo-2-nitro-1,3-propanediol

CASRN: 35691-65-7

Agent Name: 1,2-Dibromo-2,4-dicyanobutane

CASRN: 632-79-1

Agent Name: Tetrabromophthalic anhydride

CASRN: 118-79-6

Agent Name: 2,4,6-Tribromophenol

CASRN: 87-10-5

Agent Name: Tribromosalan