Nomination Summary for Trigonelline (N96014)
Nominated Substances: Trigonelline
Nomination Date: 03/22/1996
Nominator: Private Individual
Rationale: One of twenty-two substances nominated as naturally occurring chemicals in the diet. Since naturally occurring chemicals in the diet have not been a focus of cancer research, it seems reasonable to investigate some of them further as possible hazards because they often occur at high concentrations in foods. In addition, since regulatory agencies are considering a change in the standard protocol from ad libitum feeding to dietary restriction, it is important to know what impact that change will have on carcinogenicity sensitivity.