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Nomination Summary for Hydralazine hydrochloride (N97014)

Nominated Substances: Hydralazine hydrochloride

Nomination Date: 06/02/1997

Nominator: Private Individual

Rationale: Hydralazine hydrochloride is used in various antihypertensive drug formulations for which several million prescriptions are written annually. It is suspected of being a carcinogen based on mutagenicity data and positive mutagenicity and carcinogenicity data in animals for structurally related compounds. There is a lack of complete and adequate 2-year bioassay data for hydralazine hydrochloride.

NTP Principles: not specified

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